144344-66-1

Basic information

• Product Name: 4-[2-tert-Butoxycarbonyl-2-(triphenyl-λ⁵-phosphanylidene)-acetyl]-nicotinic acid
• Synonyms: 4-[2-tert-Butoxycarbonyl-2-(triphenyl-λ⁵-phosphanylidene)-acetyl]-nicotinic acid
• CAS NO: 144344-66-1
• Molecular Weight: 525.541
• Mol File: 144344-66-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[2-tert-Butoxycarbonyl-2-(triphenyl-λ⁵-phosphanylidene)-acetyl]-nicotinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-tert-Butoxycarbonyl-2-(triphenyl-λ⁵-phosphanylidene)-acetyl]-nicotinic acid(144344-66-1)
• EPA Substance Registry System: 4-[2-tert-Butoxycarbonyl-2-(triphenyl-λ⁵-phosphanylidene)-acetyl]-nicotinic acid(144344-66-1)

Safety Data

• Hazardous Substances Data: 144344-66-1(Hazardous Substances Data)

Upstream product

• 4664-08-8 cinchomeronic anhydride 
• 86302-43-4 (tert-Butoxycarbonylmethylene)triphenylphosphorane 
• 603-35-0 triphenylphosphine 
• 107-59-5 tert-Butyl chloroacetate 

Downstream Products

• 144344-67-2 4-[2-tert-Butoxycarbonyl-2-(triphenyl-λ⁵-phosphanylidene)-acetyl]-nicotinic acid methyl ester 

Relevant articles and documents

Oxidation of ylide precursors to vicinal tricarbonyls. Applications in vincamine alkaloid synthesis

Attachment of carbethoxyalkyl residues to an α,β-diketo ester provides dielectrophilic species applicable to the synthesis of the vincamine alkaloids, eburnamonine and tacamonine. The required vicinal tricarbonyl aggregates were formed by oxidation of suitable ylide precursors with ozone or singlet oxygen.