1443469-92-8Relevant articles and documents
Sequential retro-ene arylation reaction of N-alkoxyenamides for the synthesis of tert -alkylamines
Miyoshi, Tetsuya,Matsuya, Syota,Tsugawa, Mikako,Sato, Shohei,Ueda, Masafumi,Miyata, Okiko
supporting information, p. 3374 - 3377 (2013/07/26)
A sequential retro-ene arylation reaction has been developed for the conversion of N-alkoxyenamides to the corresponding tert-alkylamines in good yields via the nucleophilic addition of a triarylaluminum reagent to an in situ generated N-acylketimine. The reaction is tolerant of a range of functional groups and provides facile access to a series of tert-alkylamines that would be otherwise difficult to access using conventional procedures.