14437-50-4

Basic information

• Product Name: (S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-4-methylpentanamido)-3-(1H-indol-3-yl)propanoate
• CAS NO: 14437-50-4
• Molecular Weight: 465.549
• Mol File: 14437-50-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-4-methylpentanamido)-3-(1H-indol-3-yl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-4-methylpentanamido)-3-(1H-indol-3-yl)propanoate(14437-50-4)
• EPA Substance Registry System: (S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-4-methylpentanamido)-3-(1H-indol-3-yl)propanoate(14437-50-4)

Safety Data

• Hazardous Substances Data: 14437-50-4(Hazardous Substances Data)

Upstream product

• 3397-35-1 Z-L-leucine hydroxysuccinimide ester 
• 7524-52-9 (S)-tryptophan methyl ester hydrochloride 
• 1384344-98-2 Cbz-Leu-SH 
• 4299-70-1 L-tryptophan methyl ester 
• 2018-66-8 Z-Leu-OH 
• 128254-44-4 (S)-2-Benzyloxycarbonylamino-4-methyl-pentanoic acid 2,4-bis-methanesulfonyl-naphthalen-1-yl ester 

Relevant articles and documents

Copper(ii) mediated facile and ultra fast peptide synthesis in methanol

A novel, ultrafast, mild and scalable amide bond formation strategy in methanol using simple thioacids and amines is described. The mechanism suggests that the coupling reactions are initially mediated by CuSO4· 5H2O and subsequently catalyzed by in situ generated copper sulfide. The pure peptides were isolated in satisfactory yields in less than 5 minutes. The Royal Society of Chemistry 2012.

Urea-cored peptides for anion binding and vesicle formation

Urea and urea-triazole cored peptides were synthesized and characterized. These compounds were analyzed for their potency to sense anions such as F-, Cl-, Br-, I-, H2PO4 - and HSO4 - by UV-

PREPARATION OF 2,4-BIS(METHYLSULFONYL)-1-NAPHTHYL ("BMSN") ACTIVE ESTERS AND THEIR POTENTIAL UTILITY IN PEPTIDE BOND FORMATION

A convenient synthesis of 2,4-bis(methylthio)-1-naphthol and 2,4-bis(methylsulfonyl)-1-naphthol is reported.The utility of the latter as a carboxyl-activating component in the formation of peptide bonds is also presented.