144409-60-9

Basic information

• Product Name: (4S,9aR)-4-(3,4-dimethoxyphenyl)octahydro-2H-quinolizin-2-one
• Synonyms: (4S,9aR)-4-(3,4-dimethoxyphenyl)octahydro-2H-quinolizin-2-one
• CAS NO: 144409-60-9
• Molecular Weight: 289.375
• Mol File: 144409-60-9.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: (4S,9aR)-4-(3,4-dimethoxyphenyl)octahydro-2H-quinolizin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,9aR)-4-(3,4-dimethoxyphenyl)octahydro-2H-quinolizin-2-one(144409-60-9)
• EPA Substance Registry System: (4S,9aR)-4-(3,4-dimethoxyphenyl)octahydro-2H-quinolizin-2-one(144409-60-9)

Safety Data

• Hazardous Substances Data: 144409-60-9(Hazardous Substances Data)

Upstream product

• 34418-91-2 2,3,4,5-tetrahydropyridine N-oxide 
• 112840-38-7 2-(3,4-dimethoxyphenyl)methylenecyclopropane 
• 88931-05-9 4-(3,4-dimethoxyphenyl)octahydro-1H-quinolizin-2-ol 
• 62497-24-9 (3,4-dimethoxyphenyl)propynoic acid methyl ester 
• 109-06-8 α-picoline 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 4396-01-4 isopelletierine 
• 119910-09-7 N-tert-butoxycarbonyl-2-ethoxypiperidine 
• 748157-67-7 1-(3,4-dimethoxyphenyl)-3-(trimethylsilyloxy)buta-1,3-diene 
• 80245-51-8 4-lithio-1,2-dimethoxybenzene 
• 144409-59-6 (R)-7,8,9,9a-tetrahydro-1H-quinolizin-2(6H)-one 
• 206749-06-6 1-[1-(3,4-Dimethoxy-phenyl)-3-trimethylsilanylmethyl-but-3-enyl]-6-hydroxy-piperidin-2-one 
• 206749-04-4 1-[1-(3,4-Dimethoxy-phenyl)-3-trimethylsilanylmethyl-but-3-enyl]-piperidine-2,6-dione 
• 2859-78-1 4-Bromoveratrole 

Downstream Products

• 88931-06-0 (+/-)-subcosine I 
• 89771-50-6 (+/-)-2-episubcosine II 
• 68622-78-6 (+)-subcosine I 
• 68622-77-5 (-)-Lasubine I 
• 88931-04-8 (2RS,4RS,9aSR)-4-(3,4-dimethoxyphenyl)octahydro-2H-quinolizin-2-ol 
• 89771-49-3 (±)-lasubine II 
• 88931-05-9 4-(3,4-dimethoxyphenyl)octahydro-1H-quinolizin-2-ol 

Relevant articles and documents

α-C-H Bond Functionalization of Unprotected Alicyclic Amines: Lewis-Acid-Promoted Addition of Enolates to Transient Imines

Enolizable cyclic imines, obtained in situ from their corresponding lithium amides by oxidation with simple ketone oxidants, are readily alkylated with a range of enolates to provide mono- and polycyclic β-aminoketones in a single operation, including the natural product (±)-myrtine. Nitrile anions also serve as competent nucleophiles in these transformations, which are promoted by BF3 etherate. β-Aminoesters derived from ester enolates can be converted to the corresponding β-lactams.

Catalytic Dearomatization Approach to Quinolizidine Alkaloids: Five Step Total Synthesis of (±)-Lasubine II

A series of high-yielding silver(I)-catalyzed cyclization reactions of pyridine-, isoquinoline-, and pyrazine-ynones are described. The operationally simple and mild reaction conditions are a significant improvement over previously reported thermal cycliz

Synthetic applications of sulfur-substituted indolizidines and quinolizidines

Starting from the sulfur-substituted indolizidines and quinolizidines, a few useful synthetic transformations have been developed and the synthesis of some natural products including indolizidine 209D, epimyrtine, lasubine II, 8a-epi-dendroprimine, and 5-