1444223-90-8

Basic information

• Product Name: 2-methyl-2-(2-nitrobenzamido)butanoic acid
• Synonyms: 2-methyl-2-(2-nitrobenzamido)butanoic acid
• CAS NO: 1444223-90-8
• Molecular Weight: 266.254
• Mol File: 1444223-90-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-methyl-2-(2-nitrobenzamido)butanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-2-(2-nitrobenzamido)butanoic acid(1444223-90-8)
• EPA Substance Registry System: 2-methyl-2-(2-nitrobenzamido)butanoic acid(1444223-90-8)

Safety Data

• Hazardous Substances Data: 1444223-90-8(Hazardous Substances Data)

Upstream product

• 1444223-97-5 methyl 2-methyl-2-(2-nitrobenzamido)butanoate 
• 156032-14-3 (±)-2-methyl-2-aminobutanoic acid methyl ester hydrochloride 
• 610-14-0 2-nitrobenzyl chloride 

Downstream Products

• 1431140-96-3 C₁₈H₁₉N₃O₄S 
• 1431141-05-7 C₁₈H₁₇F₂N₃O₄S 
• 1431141-21-7 C₁₈H₁₇F₂N₃O₄S 
• 1431141-12-6 C₁₉H₂₁N₃O₄S 
• 1431140-97-4 C₁₉H₂₁N₃O₄S 
• 1431140-98-5 C₁₈H₂₅N₃O₄S 
• 1431140-99-6 C₁₈H₁₈ClN₃O₄S 
• 1431141-00-2 C₁₈H₁₈ClN₃O₄S 
• 1431141-01-3 C₁₈H₁₈ClN₃O₄S 
• 1431141-02-4 C₁₉H₁₈F₃N₃O₄S 
• 1431141-03-5 C₁₉H₂₁N₃O₅S 
• 1444223-76-0 2-(2-aminobenzamido)-2-methylbutanoic acid 
• 1431141-04-6 C₁₉H₁₉F₂N₃O₅S 

Relevant articles and documents

Identification and design of a novel series of MGAT2 inhibitors

[Acyl CoA]monoacylglycerol acyltransferase 2 (MGAT2) is of interest as a target for therapeutic treatment of diabetes, obesity and other diseases which together constitute the metabolic syndrome. In this Letter we report our discovery and optimisation of a novel series of MGAT2 inhibitors. The development of the SAR of the series and a detailed discussion around some key parameters monitored and addressed during the lead generation phase will be given. The in vivo results from an oral lipid tolerance test (OLTT) using the MGAT2 inhibitor (S)-10, shows a significant reduction (68% inhibition relative to nave, p 0.01) in plasma triacylglycerol (TAG) concentration.