1445582-60-4 Usage
Description
(S)-1-(3,5-bis(trifluoroMethyl)phenyl)-3-(1-phenylethyl)thiourea is a thiourea derivative characterized by a molecular formula of C17H14F6N2S. It features a thiourea group, which is a sulfur-containing functional group, attached to a phenylethyl group and a trifluoromethylphenyl group. (S)-1-(3,5-bis(trifluoroMethyl)phenyl)-3-(1-phenylethyl)thiourea is known for its diverse biological activities and is utilized in medicinal chemistry for the synthesis of various pharmaceuticals. The stereochemistry of this compound, denoted by the (S) prefix, signifies a specific spatial arrangement of atoms that can influence its biological activity and interactions with other molecules.
Uses
Used in Medicinal Chemistry:
(S)-1-(3,5-bis(trifluoroMethyl)phenyl)-3-(1-phenylethyl)thiourea is used as a building block for the synthesis of pharmaceuticals due to its unique structure and properties. Its diverse biological activities make it a promising candidate for the development of new drugs.
Used in Drug Development:
In the pharmaceutical industry, (S)-1-(3,5-bis(trifluoroMethyl)phenyl)-3-(1-phenylethyl)thiourea is used as a precursor compound for the creation of novel therapeutic agents. Its specific spatial arrangement of atoms, as indicated by the (S) prefix, can be crucial in determining the effectiveness and selectivity of the resulting drugs.
Used in Research and Development:
Academic and industrial research labs utilize (S)-1-(3,5-bis(trifluoroMethyl)phenyl)-3-(1-phenylethyl)thiourea as a key compound in studying the structure-activity relationships of thiourea-based pharmaceuticals. This helps in understanding the underlying mechanisms of action and optimizing the drug design process.
Check Digit Verification of cas no
The CAS Registry Mumber 1445582-60-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,4,5,5,8 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1445582-60:
(9*1)+(8*4)+(7*4)+(6*5)+(5*5)+(4*8)+(3*2)+(2*6)+(1*0)=174
174 % 10 = 4
So 1445582-60-4 is a valid CAS Registry Number.
1445582-60-4Relevant articles and documents
Asymmetric Hydroazidation of Nitroalkenes Promoted by a Secondary Amine-Thiourea Catalyst
Bellavista, Tiziana,Meninno, Sara,Lattanzi, Alessandra,Della Sala, Giorgio
, p. 3365 - 3373 (2015)
Chiral β-nitro azides are obtained by asymmetric addition of azides to nitroalkenes, with an enantioselectivity of up to 82% ee. The reaction, promoted by an easily accessible secondary amine-thiourea catalyst, is performed with azidotrimethylsilane in th