1445651-90-0Relevant articles and documents
SCREENING OF CONJUGATED ANTIBODIES
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, (2015/12/23)
Provided is a method for the functionalization of immunoglobulins through the use of transglutaminase, including methods for screening functionalized antibodies for characteristics of interest, antibody compositions comprising a plurality of functionalized antibodies, and functionalized antibodies with rodent constant regions.
ENZYMATIC CONJUGATION OF POLYPEPTIDES
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, (2015/01/07)
The present application relates to methods for the enzymatic functionalization of immunoglobulins, in particular with drugs. Also disclosed herein are linking reagents, functionalized antibodies, pharmaceutical compositions, and method of treating disease and/or conditions.
Mercaptoamides as histone deacetylase inhibitors
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Page/Page column 35, (2010/10/20)
Mercaptoamide compounds, represented by Formulas (IA), (IB), (IIA), and (IIB): or a pharmaceutically acceptable salt thereof, inhibit histone deacetylase enzyme and are useful for the treatment and/or prevention of various infections, cancerous diseases, and conditions.