14463-68-4 Usage
Description
2-Naphthyl Phosphate Monosodium Salt is an organic compound with the chemical formula C10H9Na2O4P. It is a white crystalline solid that is soluble in water and slightly soluble in organic solvents. 2-NAPHTHYL PHOSPHATE MONOSODIUM SALT is known for its potential applications in various fields, particularly in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
2-Naphthyl Phosphate Monosodium Salt is used as a reagent/reactant for the preparation of mono, di, and tri-mannopyranosyl phosphates. These compounds serve as mannose-α1-phosphate prodrugs, which have potential therapeutic applications in treating CDG-Ia (Carbohydrate-Deficient Glycoprotein Syndrome Type Ia), a genetic disorder characterized by the underproduction of specific glycoproteins.
Form
Powder
Purification Methods
Recrystallise it from H2O (10mL) containing NaCl (0.4g). The salt is collected by centrifugation and dried in a vacuum desiccator, m 203-205o (partially resolidifies and re-melts at 244o). It crystallises from MeOH (m 222-223o). The free acid is recrystallised several times by addition of 2.5 parts of hot CHCl3 to a hot solution of the free acid (1 part) in Me2CO (1.3 parts), m 177-178o. [Friedman & Seligmann J Am Chem Soc 73 5292 1951, Chanley & Feaggeson J Am Chem Soc 77 4002 1955, Beilstein 6 H 647, 6 III 2989, 6 IV 428.] See also entry on p 688 in Chapter 6.
Check Digit Verification of cas no
The CAS Registry Mumber 14463-68-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,4,6 and 3 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 14463-68:
(7*1)+(6*4)+(5*4)+(4*6)+(3*3)+(2*6)+(1*8)=104
104 % 10 = 4
So 14463-68-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H9O4P.Na.H2O/c11-15(12,13)14-10-6-5-8-3-1-2-4-9(8)7-10;;/h1-7H,(H2,11,12,13);;1H2/q;+1;/p-1
