144630-67-1Relevant articles and documents
Reaction of N-(4,4-Diethoxybutyl)phosphamides with Chloro(diphenyl)phosphine. Synthesis of 2-(Diphenylphosphoryl)pyrrolidines
Burilov, A. R.,Gazizov, A. S.,Kuznetsova, E. A.,Pudovik, M. A.,Smolobochkin, A. V.,Turmanov, R. A.
, (2020)
Abstract: The reaction of N-(4,4-diethoxybutyl)phosphamides with chloro(diphenyl)phosphine in chloroform in the presence of acetic acid gave previously unknown 2-(diphenylphosphoryl)pyrrolidines, and hydrolysis of the latter afforded 2-(diphenylphosphoryl
First synthesis and pharmacological evaluation of benzoindolizidine and benzoquinolizidine analogues of α- and β-peltatin
Couture, Axel,Deniau, Eric,Grandclaudon, Pierre,Lebrun, Stephane,Leonce, Stephane,Renard, Pierre,Pfeiffer, Bruno
, p. 2113 - 2125 (2007/10/03)
The benzoindolizidine and-quinolizidine analogues of α- and β-peltatin were designed and synthesized by two different synthetic routes involving as the key step the Bischler-Napieralski cyclization of suitably substituted N-acyl-2-arylmethylpyrrolidine and -piperidine derivatives. The in vitro biological activity of these analogues as well as some of their derivatives was subsequently evaluated. Copyright (C) 2000 Elsevier Science Ltd.
A new route to ene carbamates, precursors to benzoindolizinones through sequential asymmetric hydrogenation and cyclization
Couture, Axel,Deniau, Eric,Lebrun, Stephane,Grandclaudon, Pierre,Carpentier, Jean-Francois
, p. 1403 - 1407 (2007/10/03)
New pyrrolidine-based ene carbamates have been efficiently synthesized and the first example of asymmetric hydrogenation of this kind of substrate is reported, leading to the preparation of 2-arylmethylpyrrolidine precursors to benzoindolizinones in high