144631-04-9Relevant articles and documents
Synthesis of isoquinoline alkaloids through a 10-membered lactam obtained by radical macrocyclisation
Lamas, Carlos,Saa, Carlos,Castedo, Luis,Dominguez, Domingo
, p. 5653 - 5654 (2007/10/02)
A new versatile method for the synthesis of isoquinoline alkaloids 3 and 5 is based on transannular cyclisation of a key macrocycle 2b obtained by an intramolecular addition of an aryl radical to a trimethylsilylacetylene.