1446419-88-0

Basic information

• Product Name: C₂₈H₃₄N₄O₅S
• Synonyms: C₂₈H₃₄N₄O₅S
• CAS NO: 1446419-88-0
• Molecular Weight: 538.668
• Mol File: 1446419-88-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₈H₃₄N₄O₅S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₃₄N₄O₅S(1446419-88-0)
• EPA Substance Registry System: C₂₈H₃₄N₄O₅S(1446419-88-0)

Safety Data

• Hazardous Substances Data: 1446419-88-0(Hazardous Substances Data)

Upstream product

• 117997-81-6 5-(benzyloxy)-2-(tert-butoxycarbonylamino)-5-oxopentanoic acid 
• 87691-88-1 3-(1-piperazinyl)-1,2-benzisothiazole hydrochloride 

Downstream Products

• 1453417-04-3 C₂₃H₂₆N₄O₃S*C₂HF₃O₂ 
• 1446420-10-5 C₃₅H₃₈N₈O₃S₃ 
• 1446420-09-2 C₃₅H₃₈N₈O₄S₂ 
• 1446420-08-1 C₃₅H₃₈N₈O₃S₃ 
• 1446420-07-0 C₃₅H₃₈N₈O₄S₂ 
• 1446420-06-9 C₃₅H₃₈N₈O₃S₃ 
• 1446420-05-8 C₃₅H₃₈N₈O₄S₂ 
• 1446419-96-0 C₃₄H₃₅BrN₈O₃S₂ 
• 1446419-95-9 C₃₄H₃₅BrN₈O₂S₃ 
• 1446419-94-8 C₃₄H₃₅BrN₈O₃S₂ 
• 1446419-99-3 C₃₄H₃₅ClN₈O₂S₃ 
• 1446420-00-3 C₃₄H₃₅ClN₈O₃S₂ 
• 1446419-97-1 C₃₄H₃₅ClN₈O₂S₃ 
• 1446420-03-6 C₃₄H₃₅FN₈O₂S₃ 

Relevant articles and documents

Tert-Butyl 1,5-bis(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)-1,5- dioxopentan-2-ylcarbamate urea/thiourea derivatives as potent H +/K+-ATPase inhibitors

Amino acids are known to possess variable efficacy against ulceration. Considering the good antiulcer activity of amino acids, a series of urea/thiourea derivatives of glutamic acid conjugated benzisothiazole analogue 3a-u with various substituents on aryl ring were synthesized, spectroscopically characterized and evaluated for in vitro H+/K+-ATPase inhibition. Majority of the compounds possessed potency compared to that of omeprazole, a reference drug. In particular, methoxy derivatives 3p-u were the most active compounds possessing a significant 15-fold increase for para substituent thus, contributing positively to gastric H+/K +-ATPase inhibition.