1446486-55-0

Basic information

• Product Name: 2,3-bis(3-chlorophenyl)benzofuran
• Synonyms: 2,3-bis(3-chlorophenyl)benzofuran
• CAS NO: 1446486-55-0
• Molecular Weight: 339.221
• Mol File: 1446486-55-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2,3-bis(3-chlorophenyl)benzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-bis(3-chlorophenyl)benzofuran(1446486-55-0)
• EPA Substance Registry System: 2,3-bis(3-chlorophenyl)benzofuran(1446486-55-0)

Safety Data

• Hazardous Substances Data: 1446486-55-0(Hazardous Substances Data)

Upstream product

• 64150-61-4 dibromobenzofuran 
• 63503-60-6 3-chlorophenylboronic acid 
• 271-89-6 1-benzofurane 
• 108-37-2 1-bromo-3-chlorobenzene 
• 5216-30-8 1,2-bis(3-chlorophenyl)ethyne 
• 108-95-2 phenol 

Relevant articles and documents

Au-catalyzed synthesis of benzofurans from phenols and alkynes using molecular oxygen

An efficient Au-catalyzed transformation for the synthesis of benzofurans from phenols and alkynes using molecular oxygen has been developed. The reaction proceeds smoothly with commercially available, eco-friendly oxidant and affords the products in moderate to good yields. This reaction is a facile approach for the formation of C - C and C-O bonds.

Direct arylation of benzo[b]furan and other benzo-fused heterocycles

The direct arylation of benzo[b]furan, benzo[b]thiophene, and indole has been studied by using aromatic bromides as the aryl source. The protocol employing common reagents and a Pd catalyst has led to the regioselective arylation of these heterocycles at the 2-position. A range of functional groups were tolerated, providing quick access to a variety of arylated benzo-fused heterocycles that would be accessible more elaborately using classical synthetic strategies. This is the first systematic study of the direct arylation of benzo[b]-furan.