144664-09-5 Usage
General Description
(S)-2-Chloro-mandelamide, also known as (S)-2-chloro-2-phenylacetamide, is an organic chemical compound with the molecular formula C9H9ClNO. This white crystalline solid is typically used as an intermediate for the synthesis of pharmaceuticals and agricultural chemicals. It has a chiral center and exists as a pair of enantiomers, with the (S)-enantiomer being the more biologically active form. (S)-2-Chloro-mandelamide is known to exhibit antimicrobial and antifungal properties, making it useful in the development of new drugs and treatments. It is also used as a building block for the synthesis of various fine chemicals and is widely employed in organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 144664-09-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,6,6 and 4 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 144664-09:
(8*1)+(7*4)+(6*4)+(5*6)+(4*6)+(3*4)+(2*0)+(1*9)=135
135 % 10 = 5
So 144664-09-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H8ClNO2/c9-6-4-2-1-3-5(6)7(11)8(10)12/h1-4,7,11H,(H2,10,12)/t7-/m1/s1
144664-09-5Relevant articles and documents
Condensation of vilsmeier salts, derived from tetraalkylureas, with α-hydroxy amide derivatives: One-pot approach to synthesize 2-dialkylamino-2-oxazolin-4-ones
Liu, Bengen,Su, Dongshan,Wei, Zhonglin,Cao, Jungang,Liang, Dapeng,Lin, Yingjie,Duan, Haifeng
supporting information, p. 249 - 252 (2017/02/10)
A novel and straightforward synthetic protocol was developed to synthesize 2-dialkylamino-2-oxazolin-4-ones from various Vilsmeier salts and α-hydroxy amides derivatives. Notably, thozalinone (3a), as a mild stimulant in tristimania and anorexic, could be synthesized simply and in a high yield using this methodology.
