1446756-52-0

Basic information

• Product Name: C₁₀H₁₆ClN₅
• CAS NO: 1446756-52-0
• Molecular Weight: 241.724
• Mol File: 1446756-52-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₀H₁₆ClN₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₀H₁₆ClN₅(1446756-52-0)
• EPA Substance Registry System: C₁₀H₁₆ClN₅(1446756-52-0)

Safety Data

• Hazardous Substances Data: 1446756-52-0(Hazardous Substances Data)

Upstream product

• 108-91-8 cyclohexylamine 
• 74-89-5 methylamine 
• 27282-86-6 6-cyclohexylamino-2,4-dichloro-1,3,5-triazine 

Relevant articles and documents

Discovery of triazines as potent, selective and orally active PDE4 inhibitors

Expanding on HTS hit 4 afforded a series of [1,3,5]triazine derivatives as novel PDE4 inhibitors. The SAR development and optimization process with the emphasis on ligand efficiency and physicochemical properties led to the discovery of compound 44 as a potent, selective and orally active PDE4 inhibitor.