14469-89-7

Basic information

• Product Name: 2,4,5-trimethoxycinnamic acid ethyl ester
• Synonyms: 2,4,5-trimethoxycinnamic acid ethyl ester
• CAS NO: 14469-89-7
• Molecular Weight: 266.294
• Mol File: 14469-89-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2,4,5-trimethoxycinnamic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,5-trimethoxycinnamic acid ethyl ester(14469-89-7)
• EPA Substance Registry System: 2,4,5-trimethoxycinnamic acid ethyl ester(14469-89-7)

Safety Data

• Hazardous Substances Data: 14469-89-7(Hazardous Substances Data)

Upstream product

• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 4460-86-0 asaraldehyde 
• 141-78-6 ethyl acetate 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 2033-24-1 cycl-isopropylidene malonate 
• 64-17-5 ethanol 
• 73490-49-0 (E)-3-(2,4,5-trimethoxyphenyl)prop-2-enoic acid 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 80152-73-4 2,2,6,6-tetramethyl-5-(2,4,5-trimethoxyphenyl)heptan-3-one 
• 80152-74-5 2,2,5,5-tetramethyl-4-(2,4,5-trimethoxyphenylmethyl)hexan-3-one 
• 80152-71-2 ethyl 4,4-dimethyl-3-(2,4,5-trimethoxyphenyl)pentanoate 
• 80152-72-3 ethyl 3,3-dimethyl-2-(2,4,5-trimethoxyphenylmethyl)butanoate 
• 1264276-48-3 ethyl (Z)-3-(2,4,5-trimethoxyphenyl)-3-(4-methoxyphenyl)acrylate 
• 1380294-19-8 (E)-N-(1-(2,4,5-trimethoxyphenyl)hexa-1,5-dien-3-yl)acrylamide 
• 1380294-27-8 (E)-6-(2,4,5-trimethoxystyryl)-5,6-dihydropyridin-2(1H)-one 
• 1392497-89-0 3-(2,4,5-trimethoxyphenyl)-(2E)-2-propen-1-ol 
• 1380293-94-6 (E)-1-(2,4,5-trimethoxyphenyl)hexa-1,5-dien-3-ol 
• 1380294-02-9 (E)-1-(2,4,5-trimethoxyphenyl)hexa-1,5-dien-3-yl acrylate 
• 1380294-10-9 (E)-6-(2,4,5-trimethoxystyryl)-5,6-dihydro-2H-pyran-2-one 
• 99217-07-9 trans 2,4,5-trimethoxy cinnamaldehyde 

Relevant articles and documents

Α - Herba Asari (asarum herb) alcohol and its preparation method and application

The invention relates to (E)-3-(2,4,5-trimethoxy-phenyl)-prop-2-en-1-ol, and a preparation method and application thereof. Related (E)-3-(2,4,5-trimethoxy-phenyl)-prop-2-en-1-ol has the structural formula I shown in the specification. The related preparation method comprises: performing decarboxylation reaction on 2,4,5-trimethoxybenzaldehyde, isopropylidene malonate (meldrum's acid) and a fatty alcohol under catalytic effect of pyridine and piperidine, so as to obtain (E)-2,4,5-trimethoxycinnamate, and processing by using a reducing agent, so as to obtain (E)-3-(2,4,5-trimethoxy-phenyl)-prop-2-en-1-ol. The preparation method is simple and relatively high in yield. The related application comprises that (E)-3-(2,4,5-trimethoxy-phenyl)-prop-2-en-1-ol is applied to prepare medicines for calming, tranquilizing, resisting senile dementia, resisting convulsion, resisting epilepsy or protecting heart and cerebral vessels.

Synthesis of 2,3-syn-diarylpent-4-enamides via acyl-Claisen rearrangements of substituted cinnamyl morpholines: Application to the synthesis of magnosalicin

The acyl-Claisen rearrangement of substituted phenylacetyl chlorides and cinnamyl morpholines gives 2,3-syn-diarylpent-4-enamides. Electron-rich cinnamyl morpholines containing alkoxy substituents only reacted with phenylacetyl chlorides; replacement of t

A microwave-accelerated esterification of α,β-unsaturated acids with alkyl or aryl carbonochloridate and triethylamine in acetonitrile as a novel esterifying reagent mixture

An efficient synthesis of α,β-unsaturated esters by treatment of the corresponding acids with alkyl or aryl carbonochloridate, triethylamine, and acetonitrile was accomplished for the first time under microwave irradiation for 10 min. The esters 1b-24b were isolated in 71-97% yield.