144709-15-9

Basic information

• Product Name: [4,5-Dimethoxy-2-(1-oxo-1,2-dihydro-isoquinolin-3-yl)-phenyl]-acetic acid
• CAS NO: 144709-15-9
• Molecular Weight: 339.348
• Mol File: 144709-15-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [4,5-Dimethoxy-2-(1-oxo-1,2-dihydro-isoquinolin-3-yl)-phenyl]-acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [4,5-Dimethoxy-2-(1-oxo-1,2-dihydro-isoquinolin-3-yl)-phenyl]-acetic acid(144709-15-9)
• EPA Substance Registry System: [4,5-Dimethoxy-2-(1-oxo-1,2-dihydro-isoquinolin-3-yl)-phenyl]-acetic acid(144709-15-9)

Safety Data

• Hazardous Substances Data: 144709-15-9(Hazardous Substances Data)

Upstream product

• 38210-84-3 2-acetyl-4,5-dimethoxyphenylacetic acid 
• 3930-83-4 o-iodobenzamide 

Downstream Products

• 144709-18-2 N-methyl-3-<2-(methoxycarbonylmethyl)-4,5-dimethoxyphenyl>-1(2H)-isoquinolone 
• 144709-19-3 N-methyl-3-<2-hydroxyethyl-4,5-dimethoxyphenyl>-1(2H)-isoquinolone 
• 144709-16-0 3<2-hydroxyethyl-4,5-dimethoxyphenyl>-1(2H)-isoquinolone 
• 144709-27-3 3-<2-(methoxycarbonylmethyl)-4,5-dimethoxyphenyl>-1(2H)-isoquinolone 

Relevant articles and documents

A common and general access to berberine and benzo [c] phenanthridine alkaloids

The S(RN)1 reactions between o-iodobenzamides and the enolate anion from 2-acetyl homoveratric acid lead to key tricyclic compounds which are easily converted to either berberine or benzo [c] phenanthridine ring systems providing thus a highly-yielding and versatile access to both classes of alkaloids.