144730-05-2Relevant articles and documents
Radical-Induced Epoxide Fragmentation Chemistry. n-Bu3Sn* Radical Catalyzed Isomerization of Epoxyketones to Carbocycles
Rawal, Viresh H.,Krishnamurthy, Venkat,Fabre, Agnes
, p. 2899 - 2902 (2007/10/02)
Cyclic α,β-epoxyketones are converted to bi- or tricyclic β-hydroxyketones in the presence of n-Bu3Sn* radical.Addition of n-Bu3Sn* to carbonyl group gives a ketyl radical that triggers the epoxide fragmentation which is then followed by a 1,5-hydrogen ab