144744-45-6

Basic information

• Product Name: (3S,5R,6S)-5,6-Diphenyl-3-(4-trifluoromethyl-phenyl)-morpholin-2-one
• Synonyms: (3S,5R,6S)-5,6-Diphenyl-3-(4-trifluoromethyl-phenyl)-morpholin-2-one
• CAS NO: 144744-45-6
• Molecular Weight: 397.397
• Mol File: 144744-45-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3S,5R,6S)-5,6-Diphenyl-3-(4-trifluoromethyl-phenyl)-morpholin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,5R,6S)-5,6-Diphenyl-3-(4-trifluoromethyl-phenyl)-morpholin-2-one(144744-45-6)
• EPA Substance Registry System: (3S,5R,6S)-5,6-Diphenyl-3-(4-trifluoromethyl-phenyl)-morpholin-2-one(144744-45-6)

Safety Data

• Hazardous Substances Data: 144744-45-6(Hazardous Substances Data)

Upstream product

• 23364-44-5 (1S,2R)-2-Amino-1,2-diphenylethanol 

Downstream Products

• 144789-75-3 (S)-2-amino-2-(4-(trifluoromethyl)phenyl)acetic acid 
• 144789-73-1 (R)-<(p-Trifluoromethyl)phenyl>glycine 

Relevant articles and documents

Synthesis of Optically Active Arylglycines by Photolysis of Optically Active (β-Hydroxyamino) Carbene-Chromium(0) Complexes

Photolysis of chromium complexes having the optically active amino alcohol (1R,2S)-(-)- or (1S,2R)-(+)-2-amino-1,2-diphenylethanol as the amino group produced aryl-substituted oxazinones in good yield with reasonable diastereoselectivity.Facile separation of diastereoisomers followed by mild reductive cleavage produced several arylglycines, having either electron-donating or withdrawing groups on the aromatic ring, in good overall yield and with excellent enantiomeric excess.