144750-42-5 Usage
Description
CLOPIDOGREL RELATED COMPOUND A (20 MG) ((S)-(O-CHLOROPHENYL)-6,7-DIHYDROTHIENO[3,2-C]PYRI-DINE-5(4H)-ACETIC ACID, HYDROCHLORIDE) is a hydrochloride salt of a metabolite of the drug Clopidogrel. It is an organic compound with potential pharmaceutical applications.
Uses
Used in Pharmaceutical Industry:
CLOPIDOGREL RELATED COMPOUND A (20 MG) ((S)-(O-CHLOROPHENYL)-6,7-DIHYDROTHIENO[3,2-C]PYRI-DINE-5(4H)-ACETIC ACID, HYDROCHLORIDE) is used as an impurity reference substance for the development and quality control of Clopidogrel, a widely prescribed antiplatelet medication. It helps in ensuring the safety, efficacy, and quality of Clopidogrel products by providing a reference for impurity identification and quantification.
Used in Research and Development:
In the field of research and development, CLOPIDOGREL RELATED COMPOUND A (20 MG) ((S)-(O-CHLOROPHENYL)-6,7-DIHYDROTHIENO[3,2-C]PYRI-DINE-5(4H)-ACETIC ACID, HYDROCHLORIDE) serves as a valuable compound for studying the properties, interactions, and potential applications of Clopidogrel and its metabolites. This can lead to a better understanding of the drug's mechanism of action, as well as the development of new therapeutic strategies and drug candidates.
Please note that the provided materials do not mention any specific uses of Glycerol. The information given is about Clopidogrel Carboxylic Acid Hydrochloride, which is the hydrochloride salt of a metabolite of the drug Clopidogrel.
Check Digit Verification of cas no
The CAS Registry Mumber 144750-42-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,7,5 and 0 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 144750-42:
(8*1)+(7*4)+(6*4)+(5*7)+(4*5)+(3*0)+(2*4)+(1*2)=125
125 % 10 = 5
So 144750-42-5 is a valid CAS Registry Number.
InChI:InChI=1S/C15H14ClNO2S.ClH/c16-12-4-2-1-3-11(12)14(15(18)19)17-7-5-13-10(9-17)6-8-20-13;/h1-4,6,8,14H,5,7,9H2,(H,18,19);1H/t14-;/m0./s1
144750-42-5Relevant articles and documents
Synthesis and characterization of impurity B of S-(+)-clopidogrel bisulfate: An antiplatelet
Reddy, K. Tatendra,Kumar, K. Suneel,Omprakash,Dubey
, p. 1387 - 1396 (2013/05/22)
S-(+)-Clopidogrel bisulfate [(S-(+)-methyl 2-(2-chlorophenyl)-2-(6, 7-dihydrothieno[3, 2-c]pyridin-5(4H)-yl)acetate bisulfate)] is a platelet aggregation inhibitor drug. S-(+)-Clopidogrel bisulfate is prepared by different synthetic approaches in the literature. In almost all the approaches the major impurities known in the literature (A, B, and C) are also listed in the U.S. pharmacopoeia. The control of these pharmaceutical impurities is currently a critical issue to the pharmaceutical industry. In this article, a description of these impurities and their origins in the S-(+)-clopidogrel bisulfate process are presented along with the preparation of impurity B.
PROCESS FOR THE SYNTHESIS OF CLOPIDOGREL AND NEW FORMS OF PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF
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Page/Page column 51, (2008/06/13)
The present invention relates to a new process for the preparation of clopidogrel and to new polymorphic forms of clopidogrel salts, to processes for their preparation and to a pharmaceutical formulation containing the new forms.
