1447966-66-6

Basic information

• Product Name: (E)-1-(2-bromo-6-methylphenyl)-2-o-tolyldiazene
• Synonyms: (E)-1-(2-bromo-6-methylphenyl)-2-o-tolyldiazene
• CAS NO: 1447966-66-6
• Molecular Weight: 289.175
• Mol File: 1447966-66-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-1-(2-bromo-6-methylphenyl)-2-o-tolyldiazene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(2-bromo-6-methylphenyl)-2-o-tolyldiazene(1447966-66-6)
• EPA Substance Registry System: (E)-1-(2-bromo-6-methylphenyl)-2-o-tolyldiazene(1447966-66-6)

Safety Data

• Hazardous Substances Data: 1447966-66-6(Hazardous Substances Data)

Upstream product

• 584-90-7 trans-di-o-tolyl-diazene 

Relevant articles and documents

Palladium-catalyzed regioselective halogenation of aromatic azo compounds

A highly regioselective halogenation reaction of symmetrical and unsymmetrical aromatic azo compounds has been developed at room temperature or at 50 °C. In the presence of 5 mol% palladium diacetate and 0.5 equiv. of p-toluenesulfonic acid, a range of symmetrical aromatic azo compounds smoothly undergo monobromination with N-bromosuccinimide to give the corresponding unsymmetrical aromatic azo compounds in good to excellent yields with >99:1 ortho-selectivity. This chemistry has been successfully extended to unsymmetrical aromatic azo compounds, whose electronricher aryl groups prefer to be monobrominated. Moreover, replacing N-bromosuccinimide with Niodosuccinimide in the reaction allows the synthesis of monoiodinated aromatic azo compounds with >99:1 regioselectivity.