1448032-41-4

Basic information

• Product Name: 1-benzyl-4,5-dibromo-2-(4-nitrophenyl)-1H-imidazole
• Synonyms: 1-benzyl-4,5-dibromo-2-(4-nitrophenyl)-1H-imidazole
• CAS NO: 1448032-41-4
• Molecular Weight: 437.09
• Mol File: 1448032-41-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-benzyl-4,5-dibromo-2-(4-nitrophenyl)-1H-imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-4,5-dibromo-2-(4-nitrophenyl)-1H-imidazole(1448032-41-4)
• EPA Substance Registry System: 1-benzyl-4,5-dibromo-2-(4-nitrophenyl)-1H-imidazole(1448032-41-4)

Safety Data

• Hazardous Substances Data: 1448032-41-4(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 24067-17-2 4-nitrophenylboronic acid 
• 31250-80-3 1-benzyl-2,4,5-tribromo-1H-imidazole 

Downstream Products

• 5496-39-9 2-(4-nitrophenyl)-4,5-diphenyl-1H-imidazole 

Relevant articles and documents

Selective sequential cross-coupling reactions on imidazole towards neurodazine and analogues

Polysubstituted imidazoles represent a common structural motif in bioactive molecules. A modular and flexible strategy towards 2,4,5-triarylated imidazoles is reported applying a Suzuki-Miyaura cross-coupling protocol. Employing 1-protected 2,4,5-tribromoimidazole as starting material, both stepwise and one-pot protocols towards the title compounds are disclosed. The utility of the approach was demonstrated by synthesizing neurodazine, a biologically active molecule affecting neuronal cell differentiation.