1448308-25-5

Basic information

• Product Name: 3-{1-[(E)-2-(3,4-dimethylphenyl)hydrazono]ethyl}-2H-chromen-2-one
• Synonyms: 3-{1-[(E)-2-(3,4-dimethylphenyl)hydrazono]ethyl}-2H-chromen-2-one
• CAS NO: 1448308-25-5
• Molecular Weight: 306.364
• Mol File: 1448308-25-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-{1-[(E)-2-(3,4-dimethylphenyl)hydrazono]ethyl}-2H-chromen-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{1-[(E)-2-(3,4-dimethylphenyl)hydrazono]ethyl}-2H-chromen-2-one(1448308-25-5)
• EPA Substance Registry System: 3-{1-[(E)-2-(3,4-dimethylphenyl)hydrazono]ethyl}-2H-chromen-2-one(1448308-25-5)

Safety Data

• Hazardous Substances Data: 1448308-25-5(Hazardous Substances Data)

Upstream product

• 3949-36-8 3-acetylcoumarin 
• 60481-51-8 3,4-dimethylphenylhydrazine hydrochloride 
• 90-02-8 salicylaldehyde 

Downstream Products

• 1448308-43-7 diethyl 1-(3,4-dimethylphenyl)-3-(2-oxo-2H-chromen-3-yl)-1H-pyrazole-4,5-dicarboxylate 

Relevant articles and documents

Synthesis, anticancer activity and photophysical properties of novel substituted 2-oxo-2H-chromenylpyrazolecarboxylates

2-Oxo-2H-chromenylpyrazolecarboxylates (8a-h and 12a-zb) have been synthesized by [3 + 2] cycloaddition of 2H-chromenophenylhydrazones (7a-h and 11a-w) with diethyl/dimethylbut-2-ynedioates. Phenylchromeno[4,3-c]pyrazol-4(1H) -ones (13i-n) were prepared from corresponding phenylhydrazones (7a-h) with catalytic amount of piperidine in presence of pyridine as a solvent at 100°C. All the synthesized compounds (8a-h, 12a-zb and 13a-n) were screened for anticancer activity against three human cancer cell lines such as prostate (DU-145), lung adenocarcinoma (A549), and cervical (HeLa) by standard MTT assay method. Further, photophysical properties (UV and fluorescence) for these compounds were discussed.