1448423-01-5

Basic information

• Product Name: 4-(4-((tert-butyldiphenylsilyl)oxy)phenyl)-2-methylbut-3-yn-2-ol
• Synonyms: 4-(4-((tert-butyldiphenylsilyl)oxy)phenyl)-2-methylbut-3-yn-2-ol
• CAS NO: 1448423-01-5
• Molecular Weight: 414.62
• Mol File: 1448423-01-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(4-((tert-butyldiphenylsilyl)oxy)phenyl)-2-methylbut-3-yn-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-((tert-butyldiphenylsilyl)oxy)phenyl)-2-methylbut-3-yn-2-ol(1448423-01-5)
• EPA Substance Registry System: 4-(4-((tert-butyldiphenylsilyl)oxy)phenyl)-2-methylbut-3-yn-2-ol(1448423-01-5)

Safety Data

• Hazardous Substances Data: 1448423-01-5(Hazardous Substances Data)

Upstream product

• 115-19-5 2-methyl-but-3-yn-2-ol 
• 127481-94-1 1-bromo-4-[[(1,1-dimethylethyl)-diphenylsilyl]-oxy]-benzene 

Relevant articles and documents

K3PO4-KOH mixture as efficient reagent for the deprotection of 4-aryl-2-methyl-3-butyn-2-ols to terminal acetylenes

A mixture of potassium hydroxide and potassium phosphate was found to be an active reagent mixture for the cleavage of 2-hydroxypropyl-protected acetylenes. The reaction was performed in toluene at reflux temperature and gave terminal acetylenes in good to excellent yields within very short periods of time. Numerous other functional groups are tolerated. Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications for full experimental and spectral details.