1448538-36-0

Basic information

• Product Name: 3-[4-benzyl-5-(phenylsulfanyl)-4H-1,2,4-triazol-3-yl]quinoline
• Synonyms: 3-[4-benzyl-5-(phenylsulfanyl)-4H-1,2,4-triazol-3-yl]quinoline
• CAS NO: 1448538-36-0
• Molecular Weight: 408.527
• Mol File: 1448538-36-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[4-benzyl-5-(phenylsulfanyl)-4H-1,2,4-triazol-3-yl]quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[4-benzyl-5-(phenylsulfanyl)-4H-1,2,4-triazol-3-yl]quinoline(1448538-36-0)
• EPA Substance Registry System: 3-[4-benzyl-5-(phenylsulfanyl)-4H-1,2,4-triazol-3-yl]quinoline(1448538-36-0)

Safety Data

• Hazardous Substances Data: 1448538-36-0(Hazardous Substances Data)

Upstream product

• 23289-13-6 4-benzyl-4H-1,2,4-triazole-3-thiol 
• 93114-14-8 N-benzyl-2-formylhydrazinecarbothioamide 
• 622-78-6 Benzyl isothiocyanate 
• 1448538-28-0 4-benzyl-3-(benzylsulfanyl)-5-iodo-4H-1,2,4-triazole 
• 171364-85-5 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline 

Relevant articles and documents

Synthesis of 5-substituted 3-mercapto-1,2,4-triazoles via Suzuki-Miyaura reaction

3-Bromo- and 3-iodo-N,S-dibenzyl-5-mercapto-1,2,4-triazoles were prepared and demonstrated as versatile building blocks for Suzuki-Miyaura cross-coupling with aryl, heteroaryl, and vinyl boronic acid derivatives. Deprotection of the resulting coupling products provided 5-substituted-3-mercapto-1,2,4-triazoles in good overall yields. This represents a novel and convenient approach for the introduction of a 3-mercapto-1,2,4-triazole substructure into target compounds.