1448695-65-5

Basic information

• Product Name: 4-amino-5-(phenylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidine
• Synonyms: 4-amino-5-(phenylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidine
• CAS NO: 1448695-65-5
• Molecular Weight: 242.304
• Mol File: 1448695-65-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-amino-5-(phenylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-5-(phenylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidine(1448695-65-5)
• EPA Substance Registry System: 4-amino-5-(phenylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidine(1448695-65-5)

Safety Data

• Hazardous Substances Data: 1448695-65-5(Hazardous Substances Data)

Upstream product

• 882-33-7 diphenyldisulfane 
• 1448695-64-4 4-chloro-5-(phenylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidine 
• 3680-69-1 4-chloro-1H-pyrrolo[2,3-d]pyrimidine 
• 1500-85-2 7-deazaadenine 

Relevant articles and documents

Synthesis and cytostatic activity of 7-arylsulfanyl-7-deazapurine bases and ribonucleosides

A series of 7-phenylsulfanyl- or 7-(2-thienyl)sulfanyl-7-deazapurine bases bearing diverse substituents at position 6 was prepared through C-H sulfenylation of 6-chloro-7-deazapurine followed by cross-coupling or nucleophilic substitutions. The corresponding ribonucleosides (as thia-analogues of known nucleoside cytostatics) were prepared by glycosylation of 6-chloro-7-arylsulfanyl-7-deazapurines followed by the same transformations at position 6. The 7-thienylsulfanyl-7-deazapurine bases 2b-2h exerted micromolar cytostatic activities, whereas the nucleosides did not show significant biological effects. This journal is