1448795-01-4Relevant articles and documents
Selective addition of amines to 5-trifluoromethyl-2,4-dichloropyrimidine induced by Lewis acids
Richter, Daniel T.,Kath, John C.,Luzzio, Michael J.,Keene, Nandell,Berliner, Martin A.,Wessel, Matthew D.
supporting information, p. 4610 - 4612 (2013/08/23)
A variety of 2,4-diamino-pyrimidine systems can be prepared from the corresponding 2,4-dichloro-pyrimidine by sequential addition of two amines, the first adding selectively to the 4-position. In contrast it was found that 2,4-dichloro-5-trifluoromethyl-p
