1448841-96-0

Basic information

• Product Name: C₂₃H₃₃ClN₂O₂Si
• Synonyms: C₂₃H₃₃ClN₂O₂Si
• CAS NO: 1448841-96-0
• Molecular Weight: 433.066
• Mol File: 1448841-96-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₃H₃₃ClN₂O₂Si(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₃₃ClN₂O₂Si(1448841-96-0)
• EPA Substance Registry System: C₂₃H₃₃ClN₂O₂Si(1448841-96-0)

Safety Data

• Hazardous Substances Data: 1448841-96-0(Hazardous Substances Data)

Upstream product

• 28460-09-5 N,N-diethyl-4-tert-butylphenyl carbamate 
• 77332-79-7 3-chloro-4-iodopyridine 

Downstream Products

• 1448842-01-0 C₂₀H₂₄BrClN₂O₂ 
• 1448842-02-1 C₂₀H₂₄ClIN₂O₂ 
• 1448842-22-5 C₂₂H₁₈ClNO₂ 

Relevant articles and documents

Combined directed metalation-suzuki-miyaura cross coupling strategies. Synthesis of isomeric chromenopyridinones and related annulated analogues

A general strategy encompassing a Directed ortho Metalation (DoM) - Suzuki-Miyaura cross coupling and Directed remote Metalation (DreM) sequence for the synthesis of 5H-chromeno[4,3-c]pyridin-5-ones 5a-j, 5H-chromeno[3,4-b] pyridin-5-ones 6a-j, 5H-chromeno[3,4-c]pyridin-5-ones 13a-d, 12H-benzo[7,8]chromenopyridin-12-ones 16a-c, 17a-c, and pyrido[3',4':4,5] pyrano[2,3-e]indazol-5(1H)-one analogues 18, 28 is reported. Thus, using the powerful directed metalation group properties of aryl O-carbamates 9a-h, 14a-c metalation-boronation followed by Suzuki-Miyaura coupling with 3-bromopyridine affords a variety of azabiaryls 7a-i, 8a-b, 12a-c, 15a-c which, upon DreM reaction leads to several series of chromenopyridinones 5a-j, 6a-j, 13a-d and pyridonaphthopyrones 16a-c, 17a-c. The synthesis of an unusual pyridopyranoindazolone 18 is also described.