1448888-95-6Relevant articles and documents
Total synthesis of linoxepin through a palladium-catalyzed domino reaction
Tietze, Lutz F.,Duefert, Svenia-C.,Clerc, Jér?me,Bischoff, Matthias,Maa?, Christian,Stalke, Dietmar
, p. 3191 - 3194 (2013/04/23)
Convergent and elegant: Linoxepin (see picture), a new lignan with an unusual oxepin moiety, has been synthesized in only 10 steps. The protecting-group-free total synthesis includes a palladium- catalyzed Sonogashira reaction and a domino carbopalladation/Heck reaction of an allylsilane.