1449335-26-5

Basic information

• Product Name: (4-methoxy-1-methyl-1H-indol-3-yl)(phenyl)methanone
• Synonyms: (4-methoxy-1-methyl-1H-indol-3-yl)(phenyl)methanone
• CAS NO: 1449335-26-5
• Molecular Weight: 265.312
• Mol File: 1449335-26-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (4-methoxy-1-methyl-1H-indol-3-yl)(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-methoxy-1-methyl-1H-indol-3-yl)(phenyl)methanone(1449335-26-5)
• EPA Substance Registry System: (4-methoxy-1-methyl-1H-indol-3-yl)(phenyl)methanone(1449335-26-5)

Safety Data

• Hazardous Substances Data: 1449335-26-5(Hazardous Substances Data)

Upstream product

• 7556-35-6 4-methoxy-1-methyl-1H-indole 
• 201230-82-2 carbon monoxide 
• 369-57-3 benzenediazonium tetrafluoroborate 
• 98-09-9 benzenesulfonyl chloride 
• 611-73-4 Benzoylformic acid 
• 98-80-6 phenylboronic acid 
• 100-47-0 benzonitrile 

Relevant articles and documents

Synthetic method of indole-3-aromatic ketone derivative

The invention provides a novel method for an indole-3-aromatic ketone derivative. By using induction action of visible light, indole and aryl sulfonyl chloride and carbon monoxide are subjected to a reaction under normal temperature to generate indole-3-aromatic ketone, according to the novel synthetic method, the reaction mediums such as a transition-metal catalyst, an additive, acid and alkali are not required, the indole-3-aromatic ketone has good compatibility to a function group, the raw materials in the method have the advantages of simpleness and easy acquisition, and the method accords with a green chemistry scope.

Visible light-induced carbonylation of indoles with arylsulfonyl chlorides and CO

A novel and simple strategy for the visible light-induced efficient synthesis of indol-3-yl aryl ketones from readily available arylsulfonyl chlorides and indoles with CO at room temperature was developed. This metal-free protocol has good functional group tolerance and avoids the use of transition-metal catalysts, additives, and alkaline or acidic reaction medium.

Palladium-catalyzed carbonylation of indoles for synthesis of indol-3-yl aryl ketones

A novel palladium-catalyzed carbonylation of indoles with CO and aromatic boronic acids for the synthesis of indol-3-yl aryl ketones was developed. The reaction tolerates a wide range of functional groups and gives a variety of valuable indol-3-yl aryl ketones in high yields under mild conditions. (Chemical Presented).