1449388-91-3Relevant articles and documents
Anhydrides as α,β-unsaturated acyl ammonium precursors: Isothiourea-promoted catalytic asymmetric annulation processes
Robinson, Emily R. T.,Fallan, Charlene,Simal, Carmen,Slawin, Alexandra M. Z.,Smith, Andrew D.
, p. 2193 - 2200 (2013/05/22)
The asymmetric annulation of a range of α,β-unsaturated acyl ammonium intermediates, formed from isothiourea HBTM 2.1 and anhydrides with either 1,3-dicarbonyls, β-ketoesters or azaaryl ketones gives either functionalised esters (upon ring opening), dihydropyranones or dihydropyridones in good yields (up to 93%) and high enantioselectivity (up to 97% ee).
