1449427-53-5

Basic information

• Product Name: 1-ethynyl-2-({[(2E)-3-phenylprop-2-en-1-yl]oxy}methyl)benzene
• Synonyms: 1-ethynyl-2-({[(2E)-3-phenylprop-2-en-1-yl]oxy}methyl)benzene
• CAS NO: 1449427-53-5
• Molecular Weight: 248.324
• Mol File: 1449427-53-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-ethynyl-2-({[(2E)-3-phenylprop-2-en-1-yl]oxy}methyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ethynyl-2-({[(2E)-3-phenylprop-2-en-1-yl]oxy}methyl)benzene(1449427-53-5)
• EPA Substance Registry System: 1-ethynyl-2-({[(2E)-3-phenylprop-2-en-1-yl]oxy}methyl)benzene(1449427-53-5)

Safety Data

• Hazardous Substances Data: 1449427-53-5(Hazardous Substances Data)

Upstream product

• 6630-33-7 ortho-bromobenzaldehyde 
• 10602-08-1 2-ethynylbenzyl alcohol 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 77123-58-1 2-[2-(trimethylsilyl)ethynyl]benzaldehyde 

Downstream Products

• 1449427-76-2 4-(1-phenylprop-2-en-1-yl)-1H-isochromene 
• 1449427-78-4 4-(1-phenylallyl)-3-(prop-1-en-2-yl)-1H-isochromen 
• 1449427-80-8 tert-butyl(dimethyl){2-[4-(1-phenylprop-2-en-1-yl)-1H-isochromen-3-yl]phenoxy}silane 
• 1449427-57-9 tert-butyl(dimethyl)(2-{[2-({[(2E)-3-phenylprop-2-en-1-yl]oxy}methyl)phenyl]-ethynyl}phenoxy)silane 
• 1449427-44-4 1,1'-buta-1,3-diyne-1,4-diylbis[2-({[(2E)-3-phenylprop-2-en-1-yl]-oxy}methyl)benzene] 

Relevant articles and documents

[3,3]-Sigmatropic rearrangement step in the gold-catalyzed cyclization of allyl-(ortho-alkinylphenyl)methyl ethers

The gold-catalyzed conversion of allyl-(ortho-alkynylphenyl)methyl ethers was investigated, and allylated isochromenes were obtained. An optimization of the catalysis conditions with respect to different phosphane and carbene ligands on gold, different counterions, and different solvents was conducted. Subsequently, the scope and limitations of this reaction were investigated with 21 substrates. The mechanistic studies show an allylic inversion, as supported by NMR data and an X-ray crystal structure analysis, as well as an intermolecular reaction, as determined by crossover experiments. There is no competition of protodeauration even in the presence of water. All these observations differ from other related conversions and clearly indicate product formation by a [3,3]sigmatropic rearrangement in the step forming the new C-C bond. The Golden Key: Allylic inversion and crossover experiments reveal a sigmatropic rearrangement as a key step in the gold-catalyzed intramolecular allyl transfer in ortho-alkinyl benzyl allyl ethers. Copyright