1449655-53-1

Basic information

• Product Name: N-boc-2-(2-methoxyphenyl)-2,3-dihydro-4-pyridone
• Synonyms: N-boc-2-(2-methoxyphenyl)-2,3-dihydro-4-pyridone
• CAS NO: 1449655-53-1
• Molecular Weight: 303.358
• Mol File: 1449655-53-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-boc-2-(2-methoxyphenyl)-2,3-dihydro-4-pyridone(CAS DataBase Reference)
• NIST Chemistry Reference: N-boc-2-(2-methoxyphenyl)-2,3-dihydro-4-pyridone(1449655-53-1)
• EPA Substance Registry System: N-boc-2-(2-methoxyphenyl)-2,3-dihydro-4-pyridone(1449655-53-1)

Safety Data

• Hazardous Substances Data: 1449655-53-1(Hazardous Substances Data)

Upstream product

• 332940-69-9 tert-butyl 4-oxopyridine-1-carboxylate 
• 626-64-2 pyridin-4-ol 
• 762-75-4 tert-butyl formate 
• 578-57-4 2-bromoanisole 

Relevant articles and documents

Rhodium(I)-complexes catalyzed 1,4-conjugate addition of arylzinc chlorides to N-boc-4-pyridone

Rhodium(I)-complexes catalyzed the 1,4-conjugate addition of arylzinc chlorides to N-Boc-4-pyridone in the presence of chlorotrimethylsilane (TMSCl). A combination of [RhCl(C2H4)2]2 and BINAP was determined to be the most effective catalyst to promote the 1,4-conjugate addition reactions of arylzinc chlorides to N-Boc-4-pyridone. A broad scope of arylzinc reagents with both electron-withdrawing and electron-donating substituents on the aromatic ring successfully underwent 1,4-conjugate addition to N-Boc-4-pyridone to afford versatile 1,4-adducts 2-substituted- 2,3-dihydropyridones in good to excellent yields (up to 91%) and excellent ee (up to 96%) when (S)-BINAP was used as chiral ligand.