14497-27-9

Basic information

• Product Name: 5-PROPYL-FURAN-2-CARBALDEHYDE
• Synonyms: ASISCHEM D29295;5-PROPYL-FURAN-2-CARBALDEHYDE;5-propyl-2-furaldehyde(SALTDATA: FREE);5-Propyl-2-furaldehyde;2-Furancarboxaldehyde, 5-propyl-
• CAS NO: 14497-27-9
• Molecular Formula: C₈H₁₀O₂
• Molecular Weight: 138.16
• Mol File: 14497-27-9.mol
• Article Data: 6

Chemical Properties

• Melting Point: 100-101 °C
• Boiling Point: 221.6 °C at 760 mmHg
• Flash Point: 76.1 °C
• Appearance: /
• Density: 1.037 g/cm³
• Vapor Pressure: 0.106mmHg at 25°C
• Refractive Index: 1.504
• CAS DataBase Reference: 5-PROPYL-FURAN-2-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-PROPYL-FURAN-2-CARBALDEHYDE(14497-27-9)
• EPA Substance Registry System: 5-PROPYL-FURAN-2-CARBALDEHYDE(14497-27-9)

Safety Data

• Hazard Codes: Xi
• Statements: 43
• Safety Statements: 36/37
• HazardClass: IRRITANT
• Hazardous Substances Data: 14497-27-9(Hazardous Substances Data)

Usage

Description

5-PROPYL-FURAN-2-CARBALDEHYDE is an organic compound characterized by its distinct chemical structure and properties. It is a derivative of furan, a heterocyclic compound with a five-membered ring containing four carbon atoms and one oxygen atom. The presence of a propyl group and a formyl group attached to the furan ring gives 5-PROPYL-FURAN-2-CARBALDEHYDE its unique characteristics and potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
5-PROPYL-FURAN-2-CARBALDEHYDE is used as an inhibitor for the Hepatitis C virus NS5B polymerase. This application is significant because it helps in the development of antiviral drugs targeting the Hepatitis C virus, which is responsible for causing a severe liver infection that can lead to liver disease, cirrhosis, and even liver cancer.
The compound's ability to inhibit the NS5B polymerase, a key enzyme involved in the replication of the Hepatitis C virus, makes it a valuable candidate for the development of new therapeutic strategies against this viral infection. By targeting and inhibiting the NS5B polymerase, 5-PROPYL-FURAN-2-CARBALDEHYDE can potentially disrupt the virus's replication process, thereby reducing the viral load and helping in the treatment of Hepatitis C.

InChI:InChI=1/C8H10O2/c1-2-3-7-4-5-8(6-9)10-7/h4-6H,2-3H2,1H3

Upstream product

• 89114-37-4 5-(n-propyl)furfuraldehyde oxime 
• 13529-27-6 2-(diethoxymethyl)furan 
• 106-94-5 propyl bromide 
• 4229-91-8 2-propylfuran 
• 68-12-2 N,N-dimethyl-formamide 
• 1450-58-4 anti-furfuraldoxime 
• 2386-64-3 ethylmagnesium chloride 
• 126080-78-2 2-(chloromethyl)-5-(dibutoxymethyl)furan 
• 98-00-0 (2-furyl)methyl alcohol 
• 121389-55-7 tert-butyl(furan-2-ylmethoxy)dimethylsilane 

Downstream Products

• 83960-83-2 2-ethyl-3-oxocyclopent-1-enecarbaldehyde 

Relevant articles and documents

A flexible synthesis of the phytoprostanes B1 type I and II

(Chemical Equation Presented) Syntheses of the enantiomerically pure phytoprostanes B1 type I and II are described starting from furfural and n-propylfuran. Key steps include the preparation of the Freimanis (±)-hydroxycyclopentenone and Wittig

PREPARATION OF FURAN FATTY ACIDS FROM 5-(CHLOROMETHYL)FURFURAL

The present invention provides methods of making furfural fatty acids from (chloromethyl)furfural. The present invention also provides furfural fatty acids and nutritional supplements that include furfural fatty acids.

Therapeutic phenoxyalklpyridazines and intermediates therefor

Compounds of the formula STR1 wherein: R1 and R2 are independently hydrogen, halo, alkyl, alkenyl, alkoxy, hydroxy, hydroxyalkyl, hydroxyhaloalkyl, alkoxyalkyl, alkylthioalkynyl, hydroxyalkoxy, alkylthioalkyl, alkylsulfinylalkyl, alk