145-49-3 Usage
Description
1,5-Diamino-4,8-dihydroxyanthraquinone is an organic compound with the molecular formula C14H10N2O4. It is a derivative of anthraquinone, featuring two amino groups at the 1 and 5 positions, and two hydroxyl groups at the 4 and 8 positions. 1,5-DIAMINO-4,8-DIHYDROXYANTHRAQUINONE is known for its versatile chemical properties and potential applications in various industries.
Uses
1. Used in Organic Synthesis:
1,5-Diamino-4,8-dihydroxyanthraquinone is used as a building block for organic synthesis due to its reactive functional groups, which can be further modified to create a wide range of chemical compounds with diverse properties and applications.
2. Used in Pharmaceutical Industry:
1,5-Diamino-4,8-dihydroxyanthraquinone can be utilized as a starting material for the development of new pharmaceutical compounds, particularly those with potential therapeutic applications. Its unique structure allows for the design of molecules with specific biological activities, such as anti-cancer, anti-inflammatory, or anti-microbial properties.
3. Used in Dye Manufacturing:
1,5-DIAMINO-4,8-DIHYDROXYANTHRAQUINONE can also be used in the manufacturing of dyes, as its anthraquinone core and functional groups can impart vibrant colors to various substrates. It can be employed in the production of dyes for textiles, plastics, and other materials.
4. Used in Analytical Chemistry:
1,5-Diamino-4,8-dihydroxyanthraquinone can be used as a reagent or indicator in analytical chemistry, taking advantage of its chemical reactivity and potential to form complexes with various analytes.
5. Used in Material Science:
The compound's unique structure and properties can be exploited in the development of new materials with specific characteristics, such as conductivity, magnetism, or optical properties, for use in various applications, including electronics, sensors, and energy storage devices.
Safety Profile
Poison by intravenous
route. An eye irritant. Mutation data
reported. When heated to decomposition it
emits toxic fumes of NOx.
Check Digit Verification of cas no
The CAS Registry Mumber 145-49-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,4 and 5 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 145-49:
(5*1)+(4*4)+(3*5)+(2*4)+(1*9)=53
53 % 10 = 3
So 145-49-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H10N2O4/c15-5-1-3-7(17)11-9(5)13(19)12-8(18)4-2-6(16)10(12)14(11)20/h1-4,17-18H,15-16H2
145-49-3Relevant articles and documents
ANTHARQUINONE COMPOUNDS AS ANTI CANCER COMPOUNDS
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Page/Page column 18-19, (2008/06/13)
Anthraquinone compounds of the general formula (I) or a salt thereof (Formula I) in which R1 to R4 are each selected from the group consisting of H, C1-4 alkyl, X1, -NHR0N (R5)2 in which R0 is a C1-12 alkanediyl and each R5 is H or optionally substituted C1-4 alkyl, and a group of formula (II) in which at least one of R6,R7 and R8 is selected from X2 , and X2 substituted C1-4 alkyl and any others are H or C1-4 alkyl; R9 is selected from H, C1-4 alkyl, X2 and X2 substituted C1-4 alkyl; m is 0 or 1; n is 1 or 2; X1 is a halogen atom, a hydroxyl group, a C1-6 alkoxyl group, an aryloxy group or an acyloxy group; and X2 is a halogen atom, a hydroxyl group, a C1-6 alkoxyl group, an aryloxy group or an acyloxy group; provided that at least one of R1 to R4 is a group of formula (II). The N-oxides are useful prodrugs which are selectively bioreduced in hypoxic tumours to the corresponding cyclic amine derivatives. The amine compounds are cytotoxic and may be used as alkylating agents having topoisomerase II inhibiting activities in cancer therapy.
Process for the manufacture of aminohydroxyanthraquinones
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, (2008/06/13)
The invention relates to a process for the manufacture of an aminohydroxyanthraquinone of the formula STR1 wherein both of X are hydrogen or one X is --NH2 and the other is --OH and Z is hydrogen, C1 -C4 alkyl or carboxyl, with the proviso that, if Z is C1 -C4 alkyl or carboxyl, both of X must be hydrogen, which process comprises reacting a nitroanthraquinone of the formula STR2 wherein both of Y are hydrogen or one Y is --NO2 and the other is hydrogen and Z is as defined for formula (1), with the proviso that, if Z is C1 -C4 alkyl or carboxyl, both of Y must be hydrogen, in an aprotic dipolar solvent, with an alkali metal azide or alkaline earth metal azide, in the temperature range between 0° and 30° C. The reaction products are disperse dyes or intermediates for obtaining vat dyes and disperse dyes.