145004-88-2Relevant articles and documents
L-162,389: A potent orally active angiotensin II receptor antagonist with balanced affinity to both AT1 and AT2 receptor subtypes
Rivero,Kevin,Kivlighn,Zingaro,Chang,Greenlee
, p. 307 - 310 (2007/10/03)
Simple modifications made to our potent angiotensin II AT1 selective clinical candidate MK-996 provided a compound with balanced binding affinity to both the AT1 and the AT2 receptor subtype. This compound, L-162,389 is or