145013-67-8Relevant articles and documents
Divergent Syntheses of Pyridoacridine Alkaloids via Palladium-Catalyzed Reductive Cyclization with Nitro-Biarenes
Bian, Changhao,Liao, Hongze,Lin, Hou-Wen,Liu, Bo,Wang, Shuping
, p. 1905 - 1910 (2021/06/07)
A divergent and novel protocol for the preparation of both pyrido[2,3,4-kl]acridine and pyrido[4,3,2-kl]acridine alkaloids was developed. This method featured the remote palladium-catalyzed reductive cyclization with Mo(CO)6 as reductant. A wide range of substrates including three types of nitro arenes were tolerated and afforded corresponding products in good to excellent yields. This method has been successfully applied to the total synthesis of norsegoline, styelsamine C and the skeleton of necatorone.
Palladium-catalysed cross-coupling reactions of arylboronic acids with π-deficient heteroaryl chlorides
Ali,McKillop,Mitchell,Rebelo,Wallbank
, p. 8117 - 8126 (2007/10/02)
The palladium-catalysed cross-coupling reactions of arylboronic acids with a variety of π-deficient heteroaryl chlorides proceed in high yield. [1,4-Bis(diphenylphosphino)butane]palladium(II) dichloride was found to be a very satisfactory catalyst for monocyclic heteroaryl chlorides, whereas tetrakis(triphenylphosphine)palladium(O) was found to be excellent for a range of chloroquinoline derivatives.