145060-50-0

Basic information

• Product Name: Benzenepropanamine, N-[(4-methoxyphenyl)methyl]-
• CAS NO: 145060-50-0
• Molecular Formula: C17H21NO
• Molecular Weight: 255.36
• Mol File: 145060-50-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzenepropanamine, N-[(4-methoxyphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanamine, N-[(4-methoxyphenyl)methyl]-(145060-50-0)
• EPA Substance Registry System: Benzenepropanamine, N-[(4-methoxyphenyl)methyl]-(145060-50-0)

Safety Data

• Hazardous Substances Data: 145060-50-0(Hazardous Substances Data)

Upstream product

• 1027628-03-0 C₂₃H₂₄N₂O₅S 
• 2038-57-5 3-Phenylpropan-1-amine 
• 123-11-5 4-methoxy-benzaldehyde 
• 104-54-1 3-Phenylpropenol 
• 2393-23-9 4-methoxy-benzylamine 
• 171414-16-7 N-(4-methoxybenzyl)-2-nitro-N-(prop-2-yn-1-yl)benzenesulfonamide 
• 637-59-2 1-Bromo-3-phenylpropane 
• 122-97-4 3-Phenyl-1-propanol 
• 704892-79-5 N-(4-methoxybenzyl)-N-(3-phenylpropyl)-2-nitrobenzenesulfonamide 

Downstream Products

• 2038-57-5 3-Phenylpropan-1-amine 

Relevant articles and documents

Intramolecular C?H Amination of N-Alkylsulfamides by tert-Butyl Hypoiodite or N-Iodosuccinimide

1,3-Diamines are an important class of compounds that are broadly found in natural products and are also widely used as building blocks in organic synthesis. Although the intramolecular C?H amination of N-alkylsulfamide derivatives is a reliable method for the construction of 1,3-diamine structures, the majority of these methods involve the use of a transition-metal catalyst. We herein report on a new transition-metal-free method using tert-butyl hypoiodite (t-BuOI) or N-iodosuccinimide (NIS), enabling secondary non-benzylic and tertiary C?H amination reactions to proceed. The cyclic sulfamide products can be easily transformed into 1,3-diamines. Mechanistic investigations revealed that amination reactions using t-BuOI or NIS each proceed via different pathways.

Aerobic oxidation of amines catalyzed by polymer-incarcerated au nanoclusters: Effect of cluster size and cooperative functional groups in the polymer

Aerobic oxidation reaction of amines to imines catalyzed by polymer-incarcerated Au nanoclusters (PI-Au) was developed. The effect of cluster size for this oxidation reaction was carefully examined using the same polymer support. We have succeeded in preparation of various PI-Au catalysts containing different size clusters by modification of standard preparation methods. The size of clusters and their distribution were analyzed by electron microscopy. Interestingly, catalysts containing relatively larger clusters (>5 nm) showed higher activity in aerobic oxidation of amines than catalysts containing smaller clusters (13 nm) that showed much better activity for aerobic oxidation of alcohols. In addition, novel Au nanocluster catalysts immobilized on newly prepared polymer with tertiary amine groups were developed and they showed excellent activity for aerobic oxidation of amines to imines. The relation between cluster size and catalytic activity and role of tertiary amine in polymer were discussed. These catalysts could be applied to aerobic oxidative deprotection of p-methoxybenzyl groups.

A biomimetic electrocatalytic system for the atom-economical chemoselective synthesis of secondary amines

A facile one-pot oxidation-imine formation-reduction route to secondary amines can be achieved electrolytically from primary amines. This atom-economical 1ox-mediated sequence, leaving ammonia as the sole byproduct, allows the rapid chemoselect