145069-21-2

Basic information

• Product Name: 4-amino-5-methyl-1,2-benzoquinone
• Synonyms: 4-amino-5-methyl-1,2-benzoquinone
• CAS NO: 145069-21-2
• Molecular Weight: 137.138
• Mol File: 145069-21-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-amino-5-methyl-1,2-benzoquinone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-5-methyl-1,2-benzoquinone(145069-21-2)
• EPA Substance Registry System: 4-amino-5-methyl-1,2-benzoquinone(145069-21-2)

Safety Data

• Hazardous Substances Data: 145069-21-2(Hazardous Substances Data)

Upstream product

• 749819-92-9 4-amino-5-methyl-pyrocatechol 
• 860369-12-6 4-Amino-2-methoxy-5-methyl-phenol 
• 145314-94-9 4-amino-5-methylcatechol hydrochloride 
• 7732-18-5 water 
• 452-86-8 4-methyl-1,2-dihydroxybenzene 
• 68906-21-8 4-methyl-5-nitrobenzene-1,2-diol 

Relevant articles and documents

A New Oxidation Pathway of the Neurotoxin 6-Aminodopamine. Isolation and Characterisation of a Dimer with a Tetrahydroiminoethanophenoxazine Ring System.

Oxidation of the neurotoxin 6-aminodopamine (1) is known to proceed through the o-quinone 3, which undergoes intramolecular cyclisation to give 5,6-dihydroxyindole (6).In a re-examination of the reaction, we have found that at concentrations of 1 higher than 5 * 10-3 M a quite different course prevails, leading to the formation of the novel 7-amino-8-(2-aminoethyl)-3-hydroxy-2-oxo-2,3,4,10-tetrahydroiminoethanophenoxazine (7).Product 7 was formed by aerobic, chemical (persulphate, periodate) or enzymatic (tyrosinase, peroxidase/H2O2) oxidation of 1.On acetylation, 7 afforded the tetraacetate 8.Oxidation of the model compound 5-amino-4-methylcatechol (9) proceeded similarly as that of 1, to give the tetrahydrophenoxazinedione 11.