1451012-93-3Relevant articles and documents
Intramolecular aza-[4+3] cycloaddition reactions of α- halohydroxamates
Acharya, Arjun,Eickhoff, John A.,Jeffrey, Christopher S.
, p. 1825 - 1836 (2013/07/26)
Polyheterocyclic scaffolds were prepared by intramolecular aza-[4+3] cycloaddition reactions of aza-oxyallylic cations with cyclic dienes. The aza-oxyallylic cation was generated in situ by the dehydrohalogenation of α-halohydroxamates. The highly functionalized heterocyclic products undergo a variety of reactions that provide useful scaffolds for target-directed synthesis, including macrocyclic furans and polyhydroxylated azepanes. Georg Thieme Verlag Stuttgart. New York.