1451214-34-8Relevant articles and documents
Asymmetric syntheses of pyrrolidine and piperidine derivatives Via regio-and stereo-selective ring-opening reactions of chiral aziridine
Higashiyama, Kimio,Matsumura, Masataka,Kurita, Emiko,Yamauchi, Takayasu
, p. 371 - 380 (2013/08/15)
Asymmetric synthesis of cyclic β-amino alcohols (pyrrolidine and piperidine derivatives) has been achieved using a chiral aziridine as the starting material. The key step of this synthetic methodology is regio- and stereo-controlled ring-opening of the chiral aziridine with acetic acid or acetyl chloride.