145167-29-9

Basic information

• Product Name: (2R,3R,4R)-4-benzyloxymethyl-2,3-dimethylmethylenedioxy-cyclopentanone
• CAS NO: 145167-29-9
• Molecular Weight: 276.332
• Mol File: 145167-29-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2R,3R,4R)-4-benzyloxymethyl-2,3-dimethylmethylenedioxy-cyclopentanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,4R)-4-benzyloxymethyl-2,3-dimethylmethylenedioxy-cyclopentanone(145167-29-9)
• EPA Substance Registry System: (2R,3R,4R)-4-benzyloxymethyl-2,3-dimethylmethylenedioxy-cyclopentanone(145167-29-9)

Safety Data

• Hazardous Substances Data: 145167-29-9(Hazardous Substances Data)

Upstream product

• 115509-13-2 (3aR,6aR)-2,2-Dimethyl-3a,6a-dihydro-cyclopenta[1,3]dioxol-4-one 
• 23843-32-5 2,3-Isopropylidene-D-gulono-γ-lactone 
• 67642-42-6 2,3,5,6-di-O-isopropylidene-D-gulono-1,4-lactone 
• 66222-28-4 (benzyloxymethyl)tributylstannane 
• 89291-75-8 (3aR*,6aR*)-6-Benzyloxymethyl-2,2-dimethyl-4,6a-dihydro-3aH-cyclopenta[d][1,3]dioxol-4-one 

Downstream Products

• 145167-39-1 (1S,2S,3R,4R)-1-amino-4-benzyloxymethyl-2,3-dimethylmethylenedioxy-1-cyclopentanecarbonitrile 
• 143642-98-2 Dithiocarbonic acid O-[(1S,2S,3R,5R)-5-benzyloxymethyl-3-(tert-butyl-diphenyl-silanyloxy)-2-methylsulfanylthiocarboxyoxy-cyclopentyl] ester S-methyl ester 
• 143643-08-7 Benzoic acid (1S,2S)-4-(2-amino-6-benzyloxy-purin-9-yl)-2-benzyloxymethyl-cyclopentylmethyl ester 
• 143643-06-5 Benzoic acid (1S,2S)-2-benzyloxymethyl-4-(6-chloro-purin-9-yl)-cyclopentylmethyl ester 
• 143642-96-0 ((3aS,4R,6R,6aS)-6-Benzyloxymethyl-2,2-dimethyl-tetrahydro-cyclopenta[1,3]dioxol-4-yloxy)-tert-butyl-diphenyl-silane 
• 143643-10-1 Benzoic acid (1R,2R,4R)-2-benzyloxymethyl-4-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-cyclopentylmethyl ester 
• 143643-09-8 Benzoic acid (1R,2R,4R)-4-(4-amino-2-oxo-2H-pyrimidin-1-yl)-2-benzyloxymethyl-cyclopentylmethyl ester 
• 143642-97-1 (1S,2S,3R,5R)-3-Benzyloxymethyl-5-(tert-butyl-diphenyl-silanyloxy)-cyclopentane-1,2-diol 
• 143642-99-3 ((1S,4R)-4-Benzyloxymethyl-cyclopent-2-enyloxy)-tert-butyl-diphenyl-silane 
• 143643-05-4 Benzoic acid (1S,2S)-2-benzyloxymethyl-4-methanesulfonyloxy-cyclopentylmethyl ester 
• 143643-03-2 Benzoic acid (1R,2R)-2-benzyloxymethyl-4-oxo-cyclopentylmethyl ester 
• 143643-07-6 Benzoic acid (1R,2R)-4-amino-2-benzyloxymethyl-cyclopentylmethyl ester 
• 143643-04-3 Benzoic acid (1R,2R)-2-benzyloxymethyl-4-hydroxy-cyclopentylmethyl ester 
• 143643-02-1 (3R,4R)-3-Benzyloxymethyl-4-hydroxymethyl-cyclopentanone 

Relevant articles and documents

SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5)

The disclosure is directed to compounds of Formula I, Formula II, and Formula III. Methods of their use and preparation are also described.

Carbocyclic ring-enlarged oxetanocin analogues

Carbocyclic versions of 2′,3′-dideoxy-3′C-hydroxymethyl nucleosides with adenine, guanine, uracil and cytosine bases were synthesized from a common cyclopentenone precursor. The extra hydroxymethyl moiety was introduced by photochemical addition of methan