145167-88-0

Basic information

• Product Name: N,N-diisopropyl carbamic acid (1-phenylethyl) ester
• Synonyms: N,N-diisopropyl carbamic acid (1-phenylethyl) ester
• CAS NO: 145167-88-0
• Molecular Weight: 249.353
• Mol File: 145167-88-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N,N-diisopropyl carbamic acid (1-phenylethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-diisopropyl carbamic acid (1-phenylethyl) ester(145167-88-0)
• EPA Substance Registry System: N,N-diisopropyl carbamic acid (1-phenylethyl) ester(145167-88-0)

Safety Data

• Hazardous Substances Data: 145167-88-0(Hazardous Substances Data)

Upstream product

• 19009-39-3 N,N-diisopropylcarbamoyl chloride 
• 98-85-1 1-Phenylethanol 

Downstream Products

• 1257661-33-8 4,4,5,5-tetramethyl-2-(2-phenylpent-4-en-2-yl)-1,3,2-dioxaborolane 
• 782-05-8 (Z)-2,3-diphenyl-2-butene 
• 782-06-9 (E)-2,3-diphenylbutene 
• 428819-24-3 2,2'-(1-phenylethane-1,1-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) 
• 1257661-27-0 (±)-2-[1-(4-chlorophenyl)-1-phenylethyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Relevant articles and documents

Stereoselective Desymmetrization of gem-Diborylalkanes by “Trifluorination”

An efficient and general method for the chemoselective synthesis of unsymmetrical gem-diborylalkanes is reported. This method is based on a late-stage desymmetrization through nucleophilic “trifluorination”, providing chiral gem-diborylalkanes bearing a trifluoroborate group. The reaction offers a highly modular and diastereoselective approach towards the synthesis of gem-diborylcyclopropanes. The utility of the gem-diborylalkane building blocks was demonstrated by selective post-functionalization of the trifluoroborate group. These functionalizations include inter- and intra- Pd-catalyzed Suzuki–Miyaura coupling reactions.

Generation of allylic and benzylic organolithium reagents from the corresponding ester, amide, carbonate, carbamate and urea derivatives

The reaction of different allylic and benzylic non-enolisable esters or amides (1), carbonates (4), carbamates (6, 7) and ureas (8) with an excess of lithium powder and a catalytic amount of naphthalene (10%) in the presence of an electrophile [(i)PrCHO, (t)BuCHO, PhCHO, Me2CO, Et2CO, (CH2)5CO, Ph2CO, Me3SiCl] in THF at different temperatures (-78, -30 or 0°C) leads, after hydrolysis with water to the corresponding allylated or benzylated products (2).