145219-22-3

Basic information

• Product Name: 1,3-Benzenedicarboxylic acid, 2-nitro-, di-2-propenyl ester
• CAS NO: 145219-22-3
• Molecular Formula: C14H13NO6
• Molecular Weight: 291.26
• Mol File: 145219-22-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,3-Benzenedicarboxylic acid, 2-nitro-, di-2-propenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Benzenedicarboxylic acid, 2-nitro-, di-2-propenyl ester(145219-22-3)
• EPA Substance Registry System: 1,3-Benzenedicarboxylic acid, 2-nitro-, di-2-propenyl ester(145219-22-3)

Safety Data

• Hazardous Substances Data: 145219-22-3(Hazardous Substances Data)

Upstream product

• 21161-11-5 2-nitroisophthalic acid 
• 106-95-6 allyl bromide 

Downstream Products

• 1620682-66-7 1,3-diallyl-2-nitrobenzene 
• 881034-10-2 5-(cyclohexylmethylamino)-3-ethoxycarbonylmethoxythieno[3,2-b][1]benzothiophene-2-carboxylic acid methyl ester 
• 881034-18-0 5-cyclohexylamino-3-ethoxycarbonylmethoxythieno[3,2-b][1]benzothiophene-2-carboxylic acid methyl ester 

Relevant articles and documents

Palladium(0)-catalyzed intramolecular decarboxylative allylation of ortho nitrobenzoic esters

A Pd/Ag bimetallic system has been developed for the decarboxylative allylation of ortho-nitrobenzoic esters in an intramolecular fashion. In contrast to the typical sp2-sp3 cross-coupling approach which requires air and moisture sensitive preformed organometallic reagents, we provide an alternative route to the synthesis of ortho-allyl nitroarenes from the corresponding ortho-nitrobenzoic acid derivatives. The reaction proceeds through a mechanistically distinct decarboxylative metalation pathway. A cooperative reactivity of palladium and silver is crucial for the reaction outcome.

PTP1b inhibitors

This invention relates to modulating (e.g., inhibiting) protein tyrosine phosphatase 1B (PTP1B).