145301-08-2

Basic information

• Product Name: (E)-(5R,9R,13S,14S)-(+)-4,5α-Epoxy-14-hydroxy-3-methoxy-17-methyl-7-(4-nitrobenzyliden)-morphinan-6-on
• Synonyms: (E)-(5R,9R,13S,14S)-(+)-4,5α-Epoxy-14-hydroxy-3-methoxy-17-methyl-7-(4-nitrobenzyliden)-morphinan-6-on
• CAS NO: 145301-08-2
• Molecular Weight: 448.475
• Mol File: 145301-08-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-(5R,9R,13S,14S)-(+)-4,5α-Epoxy-14-hydroxy-3-methoxy-17-methyl-7-(4-nitrobenzyliden)-morphinan-6-on(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-(5R,9R,13S,14S)-(+)-4,5α-Epoxy-14-hydroxy-3-methoxy-17-methyl-7-(4-nitrobenzyliden)-morphinan-6-on(145301-08-2)
• EPA Substance Registry System: (E)-(5R,9R,13S,14S)-(+)-4,5α-Epoxy-14-hydroxy-3-methoxy-17-methyl-7-(4-nitrobenzyliden)-morphinan-6-on(145301-08-2)

Safety Data

• Hazardous Substances Data: 145301-08-2(Hazardous Substances Data)

Upstream product

• 76-42-6 Oxycodone 
• 555-16-8 4-nitrobenzaldehdye 
• 145301-02-6 (R/S,5R,7R,9R,13S,14S)-(4,5α-Epoxy-14-hydroxy-3-methoxy-17-methyl-6-oxo-7α-morphinanyl)-(4-nitrophenyl)-methanol 

Downstream Products

• 145301-30-0 (6R,6aS,8S,8aR,9aS,10R,15bS,16R,16aR,18R,18aS)-(-)-1,18;15,16-Diepoxy-5,6,6a,7,8a,9,9a,10,11,16a-decahydro-6,18a;10,15b-bis-(iminoethano)-2,14-dimethoxy-21,24-dimethyl-8-(4-nitrophenyl)-(8H,16H,18H)-dinaphtho<2,1-b:1',2'-i>xanthen-6a,9a,16a-triol 
• 145301-16-2 (6R,6aS,8S,12R,12aS)-(-)-1,12-Epoxy-5,6,6a,7,8,11-hexahydro-6a-hydroxy-6,12a-iminoethano-2-methoxy-10,15-dimethyl-8-(4-nitrophenyl)-(12H)-naphtho<2,1-g>chinolin-9-carbonsaeuremethylester 
• 145301-16-2 (6R,6aS,8R,12R,12aS)-(-)-1,12-Epoxy-5,6,6a,7,8,11-hexahydro-6a-hydroxy-6,12a-iminoethano-2-methoxy-10,15-dimethyl-8-(4-nitrophenyl)-(12H)-naphtho<2,1-g>chinolin-9-carbonsaeuremethylester 
• 145301-17-3 (6R,6aS,8S,12R,12aS)-(-)-1,12-Epoxy-5,6,6a,7,8,11-hexahydro-6a-hydroxy-6,12a-iminoethano-2-methoxy-10,15-dimethyl-8-(4-nitrophenyl)-(12H)-naphtho<2,1-g>chinolin-9-carbonsaeureethylester 
• 145301-17-3 (6R,6aS,8R,12R,12aS)-(-)-1,12-Epoxy-5,6,6a,7,8,11-hexahydro-6a-hydroxy-6,12a-iminoethano-2-methoxy-10,15-dimethyl-8-(4-nitrophenyl)-(12H)-naphtho<2,1-g>chinolin-9-carbonsaeureethylester 

Relevant articles and documents

Anellated pyridine compounds from hydrocodone and oxycodone, I: 1,12-Epoxy-6,12a-iminoethano-naphtho[2,1-g]quinolines

The 7-benzylidene compounds 5, obtained from hydrocodone (1a) and oxycodone (1b), react with methyl β-amino crotonic acid or ethyl acetoacetate and ammonium acetate in acetic acid to yield the epimeric 1,4-dihydropyridine 6 and 7, which were separated by