145354-79-6 Usage
Description
BENZOIC ACID (2S,4S,4'R)-2',2'-DIMETHYL-[4,4']BI[[1,3]DIOXOLANYL]-2-YLMETHYL ESTER is a complex organic compound with a unique chemical structure. It is characterized by its benzoic acid core, with a specific stereochemistry and a dioxolane-based biaryl structure. This molecule is known for its potential applications in the pharmaceutical industry, particularly as an intermediate in the synthesis of certain drugs.
Uses
Used in Pharmaceutical Industry:
BENZOIC ACID (2S,4S,4'R)-2',2'-DIMETHYL-[4,4']BI[[1,3]DIOXOLANYL]-2-YLMETHYL ESTER is used as an intermediate in the synthesis of Troxacitabine (T805580) for its potential anticancer activity. Troxacitabine is a nucleoside analogue that has been studied in patients with refractory lymphoproliferative diseases, demonstrating its potential in treating cancer.
In the synthesis of Troxacitabine, BENZOIC ACID (2S,4S,4'R)-2',2'-DIMETHYL-[4,4']BI[[1,3]DIOXOLANYL]-2-YLMETHYL ESTER plays a crucial role in the development of a drug that could offer new treatment options for patients suffering from various types of cancer, particularly those with refractory lymphoproliferative diseases. Its unique chemical structure allows for the creation of a nucleoside analogue with potential therapeutic benefits in cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 145354-79-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,3,5 and 4 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 145354-79:
(8*1)+(7*4)+(6*5)+(5*3)+(4*5)+(3*4)+(2*7)+(1*9)=136
136 % 10 = 6
So 145354-79-6 is a valid CAS Registry Number.
145354-79-6Relevant articles and documents
Potent Anti-HIV and Anti-HBV Activities of (-)-L-&β-Dioxolane-C and (+)-L-&β-Dioxolane-T and Their Asymmetric Syntheses.
Kim, Hea O.,Shanmuganathan, Kirupathevy,Alves, Antonio J.,Jeong, Lak S.,Beach, J. Warren,et al.
, p. 6899 - 6902 (2007/10/02)
The asymmetric syntheses of (+)-L-β-dioxolane-T and (-)-L-β-dioxolane-C were accomplished starting from 1,6-anhydro-L-β-gulopyranose, and their anti-HIV and anti-HBV activities were evaluated in human PBM cells, CEM cells and 2.2.15 cells, respectively. K