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145354-79-6

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145354-79-6 Usage

Description

BENZOIC ACID (2S,4S,4'R)-2',2'-DIMETHYL-[4,4']BI[[1,3]DIOXOLANYL]-2-YLMETHYL ESTER is a complex organic compound with a unique chemical structure. It is characterized by its benzoic acid core, with a specific stereochemistry and a dioxolane-based biaryl structure. This molecule is known for its potential applications in the pharmaceutical industry, particularly as an intermediate in the synthesis of certain drugs.

Uses

Used in Pharmaceutical Industry:
BENZOIC ACID (2S,4S,4'R)-2',2'-DIMETHYL-[4,4']BI[[1,3]DIOXOLANYL]-2-YLMETHYL ESTER is used as an intermediate in the synthesis of Troxacitabine (T805580) for its potential anticancer activity. Troxacitabine is a nucleoside analogue that has been studied in patients with refractory lymphoproliferative diseases, demonstrating its potential in treating cancer.
In the synthesis of Troxacitabine, BENZOIC ACID (2S,4S,4'R)-2',2'-DIMETHYL-[4,4']BI[[1,3]DIOXOLANYL]-2-YLMETHYL ESTER plays a crucial role in the development of a drug that could offer new treatment options for patients suffering from various types of cancer, particularly those with refractory lymphoproliferative diseases. Its unique chemical structure allows for the creation of a nucleoside analogue with potential therapeutic benefits in cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 145354-79-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,3,5 and 4 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 145354-79:
(8*1)+(7*4)+(6*5)+(5*3)+(4*5)+(3*4)+(2*7)+(1*9)=136
136 % 10 = 6
So 145354-79-6 is a valid CAS Registry Number.

145354-79-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name BENZOIC ACID (2S,4S,4'R)-2',2'-DIMETHYL-[4,4']BI[[1,3]DIOXOLANYL]-2-YLMETHYL ESTER

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:145354-79-6 SDS

145354-79-6Relevant articles and documents

Potent Anti-HIV and Anti-HBV Activities of (-)-L-&β-Dioxolane-C and (+)-L-&β-Dioxolane-T and Their Asymmetric Syntheses.

Kim, Hea O.,Shanmuganathan, Kirupathevy,Alves, Antonio J.,Jeong, Lak S.,Beach, J. Warren,et al.

, p. 6899 - 6902 (2007/10/02)

The asymmetric syntheses of (+)-L-β-dioxolane-T and (-)-L-β-dioxolane-C were accomplished starting from 1,6-anhydro-L-β-gulopyranose, and their anti-HIV and anti-HBV activities were evaluated in human PBM cells, CEM cells and 2.2.15 cells, respectively. K

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