145455-35-2

Basic information

• Product Name: L-692,585
• Synonyms: L-692,585;L-692;3-[[(2R)-2-Hydroxypropyl]amino]-3-methyl-N-[(3R)-2,3,4,5-tetrahydro-2-oxo-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-1-benzazepin-3-yl]-butanamide;3-[[(2R)-2-hydroxypropyl]amino]-3-methyl-N-[(3R)-2-oxo-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-4,5-dihydro-3H-1-benzazepin-3-yl]butanamide
• CAS NO: 145455-35-2
• Molecular Formula: C32H37N7O3
• Molecular Weight: 567.69
• Mol File: 145455-35-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.31g/cm³
• Refractive Index: 1.66
• Storage Temp.: Desiccate at -20°C
• CAS DataBase Reference: L-692,585(CAS DataBase Reference)
• NIST Chemistry Reference: L-692,585(145455-35-2)
• EPA Substance Registry System: L-692,585(145455-35-2)

Safety Data

• Hazardous Substances Data: 145455-35-2(Hazardous Substances Data)

Usage

Description

L-692,585 is a compound that exhibits potent and selective growth hormone (GH) secretory activity in various species, including humans. It has the potential to be utilized in the medical and pharmaceutical industries due to its ability to stimulate the release of growth hormone.

Uses

Used in Pharmaceutical Industry:
L-692,585 is used as a pharmaceutical agent for its potent and selective growth hormone secretory activity. L-692,585 can be utilized in the development of treatments for conditions related to growth hormone deficiency or imbalances.
Used in Medical Research:
In the field of medical research, L-692,585 can be employed as a research tool to study the effects of growth hormone secretion on various physiological processes and to develop a better understanding of the underlying mechanisms involved in growth hormone regulation.
Used in Growth Hormone Therapy:
L-692,585 can be used as a component in growth hormone therapy to help individuals with growth hormone deficiencies or those who require growth hormone support for various medical reasons, such as short stature, Turner syndrome, or chronic renal insufficiency.
Used in Sports Performance Enhancement:
Although not recommended or approved for such use, L-692,585 may potentially be misused by athletes seeking to enhance their sports performance through increased growth hormone secretion. However,

Biological Activity

Highly potent, non-peptide ghrelin receptor (GHS-R1a) agonist (K i = 0.8 nM). Increases plasma GH levels in vivo and is 2- to 2.5-fold more potent than GHRP-6.

InChI:InChI=1/C32H37N7O3/c1-21(40)19-33-32(2,3)18-29(41)34-27-17-16-24-8-4-7-11-28(24)39(31(27)42)20-22-12-14-23(15-13-22)25-9-5-6-10-26(25)30-35-37-38-36-30/h4-15,21,27,33,40H,16-20H2,1-3H3,(H,34,41)(H,35,36,37,38)/t21-,27-/m1/s1

Relevant articles and documents

Benzo-fused lactams that promote the release of growth hormone

There are disclosed certain novel compounds identified as benzo-fused lactams which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible meat products more efficient, and in humans, to increase the stature of those afflicted with a lack of a normal secretion of natural growth hormone. Growth promoting compositions containing such benzo-fused lactams as the active ingredient thereof are also disclosed.