1454648-39-5

Basic information

• Product Name: (R)-N-{1-[(S)-4-(2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-3-yl)-benzyl]-piperidin-4-yl}-2-methylamino-propionamide
• Synonyms: (R)-N-{1-[(S)-4-(2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-3-yl)-benzyl]-piperidin-4-yl}-2-methylamino-propionamide
• CAS NO: 1454648-39-5
• Molecular Weight: 410.516
• Mol File: 1454648-39-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-N-{1-[(S)-4-(2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-3-yl)-benzyl]-piperidin-4-yl}-2-methylamino-propionamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N-{1-[(S)-4-(2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-3-yl)-benzyl]-piperidin-4-yl}-2-methylamino-propionamide(1454648-39-5)
• EPA Substance Registry System: (R)-N-{1-[(S)-4-(2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-3-yl)-benzyl]-piperidin-4-yl}-2-methylamino-propionamide(1454648-39-5)

Safety Data

• Hazardous Substances Data: 1454648-39-5(Hazardous Substances Data)

Upstream product

• 1454648-92-0 1-[(S)-4-(2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-3-yl)-benzyl]-piperidin-4-ylamine 
• 1454763-43-9 1-[(S)-4-(2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-3-yl)-benzyl]-piperidin-4-ylamine 
• 13734-31-1 N-tert-butoxycarbonyl-N-methyl-(R)-alanine 

Relevant articles and documents

BENZODIOXANES FOR INHIBITING LEUKOTRIENE PRODUCTION

The present invention relates to compounds of formula (I) wherein R1 to R3, A, X and n are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.