1454661-34-7

Basic information

• Product Name: diethyl 4-((tert-butyldiphenylsilyl)oxy)-2-fluoro-2-methylbutylphosphonate
• Synonyms: diethyl 4-((tert-butyldiphenylsilyl)oxy)-2-fluoro-2-methylbutylphosphonate
• CAS NO: 1454661-34-7
• Molecular Weight: 480.632
• Mol File: 1454661-34-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl 4-((tert-butyldiphenylsilyl)oxy)-2-fluoro-2-methylbutylphosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 4-((tert-butyldiphenylsilyl)oxy)-2-fluoro-2-methylbutylphosphonate(1454661-34-7)
• EPA Substance Registry System: diethyl 4-((tert-butyldiphenylsilyl)oxy)-2-fluoro-2-methylbutylphosphonate(1454661-34-7)

Safety Data

• Hazardous Substances Data: 1454661-34-7(Hazardous Substances Data)

Upstream product

• 762-04-9 phosphonic acid diethyl ester 
• 177606-52-9 tert-butyl((3-methylbut-3-en-1-yl)oxy)diphenylsilane 

Relevant articles and documents

Silver-catalyzed radical phosphonofluorination of unactivated alkenes

We report herein a mild and catalytic phosphonofluorination of unactivated alkenes. With catalysis by AgNO3, the condensation of various unactivated alkenes with diethyl phosphite and Selectfluor reagent in CH 2Cl2/H2O/HOAc at 40 C led to the efficient synthesis of β-fluorinated alkylphosphonates with good stereoselectivity and wide functional group compatibility. A mechanism involving silver-catalyzed oxidative generation of phosphonyl radicals and silver-assisted fluorine atom transfer is proposed.