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1454681-46-9

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1454681-46-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1454681-46-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,5,4,6,8 and 1 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1454681-46:
(9*1)+(8*4)+(7*5)+(6*4)+(5*6)+(4*8)+(3*1)+(2*4)+(1*6)=179
179 % 10 = 9
So 1454681-46-9 is a valid CAS Registry Number.

1454681-46-9Downstream Products

1454681-46-9Relevant articles and documents

Facile synthesis of N-substituted amides from alkenes and amides by a Bronsted acid mediated electrophilic addition reaction

Mihara, Karin,Okada, Iku,Chiba, Kazuhiro,Kitano, Yoshikazu

, p. 1455 - 1462 (2014)

A facile and widely applicable method for the synthesis of N-substituted amides from alkenes and amides using Bronsted acids was developed. Treatment of various alkenes with amides and an alkali metal halide or methanesulfonic acid in trifluoroacetic acid afforded the corresponding N-substituted amides in good to high yield. The reaction proceeds via the direct electrophilic addition of the amides to the alkenes. Various functional groups such as ester, ether, imide, amide, and halogen were tolerated under the reaction conditions. High substrate-dependent cis stereoselectivity in the synthesis was also observed for methylenecyclohexane and methylcyclohexene derivatives possessing a substituent at the 4-position. Furthermore, a practical application of this reaction has been demonstrated by the synthesis of an intermediate of a bioactive compound on a large scale. Georg Thieme Verlag Stuttgart New York.

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