145471-53-0Relevant articles and documents
New approaches to Corynanthe alkaloids involving the conjugate addition of dialkyl malonates to unsaturated thiolactams: Synthesis of (±)-3-epi-dihydrocorynantheol
Gomez-Pardo,Desmaele,D'Angelo
, p. 6633 - 6636 (2007/10/02)
Addition of dimethyl malonate to thiolactam 8 led to a mixture of Michael adducts 9 and 10 (6:1, respectively). Compound 9 has been converted in 4 steps into (±)-3-epi-dihydrocorynantheol 16.